Pharmacokinetics of Nuciferine and N-Nornuciferine, Two Major Alkaloids From Nelumbo nucifera Leaves, in Rat Plasma and the Brain

Pharmacokinetics of Nuciferine and N-Nornuciferine, Two Major Alkaloids From Nelumbo nucifera Leaves, in Rat Plasma and the Brain

The leaf of the lotus (Nelumbo nucifera) is a natural plant resource used as both food and herbal medicine (He-Ye) in China. Alkaloids are considered the major bioactive compound of the herb and exhibit various biological activities, including anti-hyperlipidemia, anti-obesity, anti-inflammatory, an...

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Bibliographic Details
Main Authors: Lin-Hu Ye, Xiao-Xi He, Chang You, Xue Tao, Li-Sha Wang, Meng-Di Zhang, Yun-Feng Zhou, Qi Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Pharmacology
Subjects:
Nelumbo nucifera
nuciferine
N-nornuciferine
pharmacokinetics
brain microdialysis
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00902/full

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