Phenotype-Based HPLC-Q-TOF-MS/MS Coupled With Zebrafish Behavior Trajectory Analysis System for the Identification of the Antidepressant Components in Methanol Extract of Anshen Buxin Six Pills

Phenotype-Based HPLC-Q-TOF-MS/MS Coupled With Zebrafish Behavior Trajectory Analysis System for the Identification of the Antidepressant Components in Methanol Extract of Anshen Buxin Six Pills

Phenotype screening has become an important tool for the discovery of active components in traditional Chinese medicine. Anshen Buxin Six Pills (ASBX) are a traditional Mongolian medicine used for the treatment of neurosis in clinical settings. However, its antidepressant components have not been ex...

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Bibliographic Details
Main Authors: Jiani Liu, Yue Shang, Juanlan Xiao, Huirong Fan, Min Jiang, Saijun Fan, Gang Bai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Subjects:
Anshen Buxin Six Pills
anti-depression
costunolide
dehydrocostus lactone
phenotype-based screening method
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.764388/full

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