Effect of Routine Varicella Immunization on the Epidemiology and Immunogenicity of Varicella and Shingles

Varicella-zoster virus (VZV) causes varicella as a primary infection and remains latent in the ganglia until it becomes reactivated to cause herpes zoster. Individuals with varicella develop adaptive humoral and cell-mediated immunity. Compromised cell-mediated immunity is thought to contribute to t...

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Bibliographic Details
Main Authors: Naruhito Otani, Masayuki Shima, Takuma Yamamoto, Toshiomi Okuno
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/3/588