Uptake of Pharmaceutical Pollutants and Their Metabolites from Soil Fertilized with Manure to Parsley Tissues
Manure is a major source of soil and plant contamination with veterinary drugs residues. The aim of this study was to evaluate the uptake of 14 veterinary pharmaceuticals by parsley from soil fertilized with manure. Pharmaceutical content was determined in roots and leaves. Liquid chromatography cou...
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MDPI AG
2022-07-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/27/14/4378 |
| _version_ | 1797444912359145472 |
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| author | Klaudia Stando Ewa Korzeniewska Ewa Felis Monika Harnisz Sylwia Bajkacz |
| author_facet | Klaudia Stando Ewa Korzeniewska Ewa Felis Monika Harnisz Sylwia Bajkacz |
| author_sort | Klaudia Stando |
| collection | DOAJ |
| description | Manure is a major source of soil and plant contamination with veterinary drugs residues. The aim of this study was to evaluate the uptake of 14 veterinary pharmaceuticals by parsley from soil fertilized with manure. Pharmaceutical content was determined in roots and leaves. Liquid chromatography coupled with tandem mass spectrometry was used for targeted analysis. Screening analysis was performed to identify transformation products in the parsley tissues. A solid-liquid extraction procedure was developed combined with solid-phase extraction, providing recoveries of 61.9–97.1% for leaves and 51.7–95.6% for roots. Four analytes were detected in parsley: enrofloxacin, tylosin, sulfamethoxazole, and doxycycline. Enrofloxacin was detected at the highest concentrations (13.4–26.3 ng g<sup>−1</sup>). Doxycycline accumulated mainly in the roots, tylosin in the leaves, and sulfamethoxazole was found in both tissues. 14 transformation products were identified and their distribution were determined. This study provides important data on the uptake and transformation of pharmaceuticals in plant tissues. |
| first_indexed | 2024-03-09T13:18:17Z |
| format | Article |
| id | doaj.art-3fbfa7ba31bb42f5bce8ff0e4d74cad0 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T13:18:17Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-3fbfa7ba31bb42f5bce8ff0e4d74cad02023-11-30T21:32:53ZengMDPI AGMolecules1420-30492022-07-012714437810.3390/molecules27144378Uptake of Pharmaceutical Pollutants and Their Metabolites from Soil Fertilized with Manure to Parsley TissuesKlaudia Stando0Ewa Korzeniewska1Ewa Felis2Monika Harnisz3Sylwia Bajkacz4Department of Inorganic, Analytical Chemistry and Electrochemistry, Faculty of Chemistry, Silesian University of Technology, B. Krzywoustego 6 Str., 44-100 Gliwice, PolandDepartment of Engineering of Water Protection and Environmental Microbiology, Faculty of Geoengineering, University of Warmia and Mazury in Olsztyn, Prawocheńskiego 1 Str., 10-720 Olsztyn, PolandCentre for Biotechnology, Silesian University of Technology, B. Krzywoustego 8 Str., 44-100 Gliwice, PolandDepartment of Engineering of Water Protection and Environmental Microbiology, Faculty of Geoengineering, University of Warmia and Mazury in Olsztyn, Prawocheńskiego 1 Str., 10-720 Olsztyn, PolandDepartment of Inorganic, Analytical Chemistry and Electrochemistry, Faculty of Chemistry, Silesian University of Technology, B. Krzywoustego 6 Str., 44-100 Gliwice, PolandManure is a major source of soil and plant contamination with veterinary drugs residues. The aim of this study was to evaluate the uptake of 14 veterinary pharmaceuticals by parsley from soil fertilized with manure. Pharmaceutical content was determined in roots and leaves. Liquid chromatography coupled with tandem mass spectrometry was used for targeted analysis. Screening analysis was performed to identify transformation products in the parsley tissues. A solid-liquid extraction procedure was developed combined with solid-phase extraction, providing recoveries of 61.9–97.1% for leaves and 51.7–95.6% for roots. Four analytes were detected in parsley: enrofloxacin, tylosin, sulfamethoxazole, and doxycycline. Enrofloxacin was detected at the highest concentrations (13.4–26.3 ng g<sup>−1</sup>). Doxycycline accumulated mainly in the roots, tylosin in the leaves, and sulfamethoxazole was found in both tissues. 14 transformation products were identified and their distribution were determined. This study provides important data on the uptake and transformation of pharmaceuticals in plant tissues.https://www.mdpi.com/1420-3049/27/14/4378pharmaceuticalsparsleyplant metabolismplant uptaketransformation productsLC-MS/MS analysis |
| spellingShingle | Klaudia Stando Ewa Korzeniewska Ewa Felis Monika Harnisz Sylwia Bajkacz Uptake of Pharmaceutical Pollutants and Their Metabolites from Soil Fertilized with Manure to Parsley Tissues Molecules pharmaceuticals parsley plant metabolism plant uptake transformation products LC-MS/MS analysis |
| title | Uptake of Pharmaceutical Pollutants and Their Metabolites from Soil Fertilized with Manure to Parsley Tissues |
| title_full | Uptake of Pharmaceutical Pollutants and Their Metabolites from Soil Fertilized with Manure to Parsley Tissues |
| title_fullStr | Uptake of Pharmaceutical Pollutants and Their Metabolites from Soil Fertilized with Manure to Parsley Tissues |
| title_full_unstemmed | Uptake of Pharmaceutical Pollutants and Their Metabolites from Soil Fertilized with Manure to Parsley Tissues |
| title_short | Uptake of Pharmaceutical Pollutants and Their Metabolites from Soil Fertilized with Manure to Parsley Tissues |
| title_sort | uptake of pharmaceutical pollutants and their metabolites from soil fertilized with manure to parsley tissues |
| topic | pharmaceuticals parsley plant metabolism plant uptake transformation products LC-MS/MS analysis |
| url | https://www.mdpi.com/1420-3049/27/14/4378 |
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