Biomaterials in Tooth Tissue Engineering: A Review

Biomaterials play a crucial role in the field of tissue engineering. They are utilized for fabricating frameworks known as scaffolds, matrices or constructs which are interconnected porous structures that establish a cellular microenvironment required for optimal tissue regeneration. Several natur...

Full description

Bibliographic Details
Main Authors: Sarang Sharma, Dhirendra Srivastava, Shibani Grover, Vivek Sharma
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2014-01-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/3937/98-7609_E(%20_%20)_F(H)_PF1(RKH)_PFA(H)_PFA2(H)_PFA3(H)_PF2(NJH).pdf
_version_ 1819230100084752384
author Sarang Sharma
Dhirendra Srivastava
Shibani Grover
Vivek Sharma
author_facet Sarang Sharma
Dhirendra Srivastava
Shibani Grover
Vivek Sharma
author_sort Sarang Sharma
collection DOAJ
description Biomaterials play a crucial role in the field of tissue engineering. They are utilized for fabricating frameworks known as scaffolds, matrices or constructs which are interconnected porous structures that establish a cellular microenvironment required for optimal tissue regeneration. Several natural and synthetic biomaterials have been utilized for fabrication of tissue engineering scaffolds. Amongst different biomaterials, polymers are the most extensively experimented and employed materials. They can be tailored to provide good interconnected porosity, large surface area, adequate mechanical strengths, varying surface characterization and different geometries required for tissue regeneration. A single type of material may however not meet all the requirements. Selection of two or more biomaterials, optimization of their physical, chemical and mechanical properties and advanced fabrication techniques are required to obtain scaffold designs intended for their final application. Current focus is aimed at designing biomaterials such that they will replicate the local extra cellular environment of the native organ and enable cell-cell and cell-scaffold interactions at micro level required for functional tissue regeneration. This article provides an insight into the different biomaterials available and the emerging use of nano engineering principles for the construction of bioactive scaffolds in tooth regeneration.
first_indexed 2024-12-23T11:23:42Z
format Article
id doaj.art-3fc238ccf6ea404197f2d23d89e53fca
institution Directory Open Access Journal
issn 2249-782X
0973-709X
language English
last_indexed 2024-12-23T11:23:42Z
publishDate 2014-01-01
publisher JCDR Research and Publications Private Limited
record_format Article
series Journal of Clinical and Diagnostic Research
spelling doaj.art-3fc238ccf6ea404197f2d23d89e53fca2022-12-21T17:49:00ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2014-01-018130931510.7860/JCDR/2014/7609.3937Biomaterials in Tooth Tissue Engineering: A ReviewSarang Sharma0Dhirendra Srivastava1Shibani Grover2Vivek Sharma3Associate Professor, Department of Conservative Dentistry and Endodontics, ESIC Dental College and Hospital, Rohini, Delhi-85, India.Professor, Department of Oral Surgery, ESIC Dental College and Hospital, Rohini, Delhi-85, India.Professor, Department of Conservative Dentistry and Endodontics, ESIC Dental College and Hospital, Rohini, Delhi-85, India.Assistant Professor, Department of Conservative Dentistry and Endodontics, ESIC Dental College and Hospital, Rohini, Delhi-85, India.Biomaterials play a crucial role in the field of tissue engineering. They are utilized for fabricating frameworks known as scaffolds, matrices or constructs which are interconnected porous structures that establish a cellular microenvironment required for optimal tissue regeneration. Several natural and synthetic biomaterials have been utilized for fabrication of tissue engineering scaffolds. Amongst different biomaterials, polymers are the most extensively experimented and employed materials. They can be tailored to provide good interconnected porosity, large surface area, adequate mechanical strengths, varying surface characterization and different geometries required for tissue regeneration. A single type of material may however not meet all the requirements. Selection of two or more biomaterials, optimization of their physical, chemical and mechanical properties and advanced fabrication techniques are required to obtain scaffold designs intended for their final application. Current focus is aimed at designing biomaterials such that they will replicate the local extra cellular environment of the native organ and enable cell-cell and cell-scaffold interactions at micro level required for functional tissue regeneration. This article provides an insight into the different biomaterials available and the emerging use of nano engineering principles for the construction of bioactive scaffolds in tooth regeneration.https://jcdr.net/articles/PDF/3937/98-7609_E(%20_%20)_F(H)_PF1(RKH)_PFA(H)_PFA2(H)_PFA3(H)_PF2(NJH).pdfscaffoldbiomaterialstooth regenerationpolymersnanotechnology
spellingShingle Sarang Sharma
Dhirendra Srivastava
Shibani Grover
Vivek Sharma
Biomaterials in Tooth Tissue Engineering: A Review
Journal of Clinical and Diagnostic Research
scaffold
biomaterials
tooth regeneration
polymers
nanotechnology
title Biomaterials in Tooth Tissue Engineering: A Review
title_full Biomaterials in Tooth Tissue Engineering: A Review
title_fullStr Biomaterials in Tooth Tissue Engineering: A Review
title_full_unstemmed Biomaterials in Tooth Tissue Engineering: A Review
title_short Biomaterials in Tooth Tissue Engineering: A Review
title_sort biomaterials in tooth tissue engineering a review
topic scaffold
biomaterials
tooth regeneration
polymers
nanotechnology
url https://jcdr.net/articles/PDF/3937/98-7609_E(%20_%20)_F(H)_PF1(RKH)_PFA(H)_PFA2(H)_PFA3(H)_PF2(NJH).pdf
work_keys_str_mv AT sarangsharma biomaterialsintoothtissueengineeringareview
AT dhirendrasrivastava biomaterialsintoothtissueengineeringareview
AT shibanigrover biomaterialsintoothtissueengineeringareview
AT viveksharma biomaterialsintoothtissueengineeringareview