Pseudomembranous colitis in a patient with lamotrigine-induced drug rash with eosinophilia and systemic symptoms syndrome
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a hypersensitivity reaction with rash, fever and multiorgan dysfunction potentially lethal in up to 10% of cases. It often affects liver function, but it can also affect kidney, lungs, and heart. Severe gastrointestinal involv...
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| Format: | Article |
| Language: | English |
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MDPI AG
2016-08-01
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| Series: | Gastroenterology Insights |
| Subjects: | |
| Online Access: | http://www.pagepress.org/journals/index.php/gi/article/view/6491 |
| _version_ | 1818019097485508608 |
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| author | Manuel Soria Orozco Eduardo Martín Nares Alvaro López Iñiguez Sandra Gónzalez Saldaña Lorena Valerdi Contreras Jair Abdiel Toro Guerrero |
| author_facet | Manuel Soria Orozco Eduardo Martín Nares Alvaro López Iñiguez Sandra Gónzalez Saldaña Lorena Valerdi Contreras Jair Abdiel Toro Guerrero |
| author_sort | Manuel Soria Orozco |
| collection | DOAJ |
| description | Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a hypersensitivity reaction with rash, fever and multiorgan dysfunction potentially lethal in up to 10% of cases. It often affects liver function, but it can also affect kidney, lungs, and heart. Severe gastrointestinal involvement is rare. We present a case of a 31-year-old hispanic woman with pseudomembranous colitis associated with lamotrigine-induced DRESS syndrome. To the best of our knowledge, this is the fourth reported case of severe involvement of the gastrointestinal tract and the first to report pseudomembranous colitis in the setting of DRESS syndrome. |
| first_indexed | 2024-04-14T07:47:45Z |
| format | Article |
| id | doaj.art-3fc55ba6ee124d26a13164625fc5d58e |
| institution | Directory Open Access Journal |
| issn | 2036-7414 2036-7422 |
| language | English |
| last_indexed | 2024-04-14T07:47:45Z |
| publishDate | 2016-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gastroenterology Insights |
| spelling | doaj.art-3fc55ba6ee124d26a13164625fc5d58e2022-12-22T02:05:17ZengMDPI AGGastroenterology Insights2036-74142036-74222016-08-017110.4081/gi.2016.64913498Pseudomembranous colitis in a patient with lamotrigine-induced drug rash with eosinophilia and systemic symptoms syndromeManuel Soria Orozco0Eduardo Martín Nares1Alvaro López Iñiguez2Sandra Gónzalez Saldaña3Lorena Valerdi Contreras4Jair Abdiel Toro Guerrero5Department of Internal Medicine, Civil Hospital Fray Antonio Alcalde, Guadalajara, JaliscoDepartment of Internal Medicine, Civil Hospital Fray Antonio Alcalde, Guadalajara, JaliscoDepartment of Internal Medicine, Civil Hospital Fray Antonio Alcalde, Guadalajara, JaliscoDepartment of Internal Medicine, Civil Hospital Fray Antonio Alcalde, Guadalajara, JaliscoDepartment of Internal Medicine, Civil Hospital Fray Antonio Alcalde, Guadalajara, JaliscoDepartment of Pathology, Civil Hospital Fray Antonio Alcalde, Guadalajara, JaliscoDrug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a hypersensitivity reaction with rash, fever and multiorgan dysfunction potentially lethal in up to 10% of cases. It often affects liver function, but it can also affect kidney, lungs, and heart. Severe gastrointestinal involvement is rare. We present a case of a 31-year-old hispanic woman with pseudomembranous colitis associated with lamotrigine-induced DRESS syndrome. To the best of our knowledge, this is the fourth reported case of severe involvement of the gastrointestinal tract and the first to report pseudomembranous colitis in the setting of DRESS syndrome.http://www.pagepress.org/journals/index.php/gi/article/view/6491DRESS syndromemultiorgan involvementpseudomembranous colitislamotrigineanticonvulsant hypersensitivity syndrome |
| spellingShingle | Manuel Soria Orozco Eduardo Martín Nares Alvaro López Iñiguez Sandra Gónzalez Saldaña Lorena Valerdi Contreras Jair Abdiel Toro Guerrero Pseudomembranous colitis in a patient with lamotrigine-induced drug rash with eosinophilia and systemic symptoms syndrome Gastroenterology Insights DRESS syndrome multiorgan involvement pseudomembranous colitis lamotrigine anticonvulsant hypersensitivity syndrome |
| title | Pseudomembranous colitis in a patient with lamotrigine-induced drug rash with eosinophilia and systemic symptoms syndrome |
| title_full | Pseudomembranous colitis in a patient with lamotrigine-induced drug rash with eosinophilia and systemic symptoms syndrome |
| title_fullStr | Pseudomembranous colitis in a patient with lamotrigine-induced drug rash with eosinophilia and systemic symptoms syndrome |
| title_full_unstemmed | Pseudomembranous colitis in a patient with lamotrigine-induced drug rash with eosinophilia and systemic symptoms syndrome |
| title_short | Pseudomembranous colitis in a patient with lamotrigine-induced drug rash with eosinophilia and systemic symptoms syndrome |
| title_sort | pseudomembranous colitis in a patient with lamotrigine induced drug rash with eosinophilia and systemic symptoms syndrome |
| topic | DRESS syndrome multiorgan involvement pseudomembranous colitis lamotrigine anticonvulsant hypersensitivity syndrome |
| url | http://www.pagepress.org/journals/index.php/gi/article/view/6491 |
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