Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and industry funding
<p>Abstract</p> <p>The Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) is a prospective, randomized, multicenter clinical trial of carotid endarterectomy (CEA) versus carotid artery stenting (CAS) as prevention for stroke in patients with symptomatic stenosis...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2001-07-01
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| Series: | Current Controlled Trials in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | http://cvm.controlled-trials.com/content/2/4/160 |
| _version_ | 1818327265787772928 |
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| author | Brott Thomas G Howard George Howard Virginia J Hobson Robert W Roubin Gary S Ferguson Robert DG |
| author_facet | Brott Thomas G Howard George Howard Virginia J Hobson Robert W Roubin Gary S Ferguson Robert DG |
| author_sort | Brott Thomas G |
| collection | DOAJ |
| description | <p>Abstract</p> <p>The Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) is a prospective, randomized, multicenter clinical trial of carotid endarterectomy (CEA) versus carotid artery stenting (CAS) as prevention for stroke in patients with symptomatic stenosis greater than or equal to 50%. CREST is sponsored by the US National Institute of Neurological Disorders and Stroke (NINDS) of the US National Institutes of Health (NIH), with additional support by a device manufacturer, and will provide data to the US Food and Drug Administration (FDA) for evaluation of a stent device. Because of budget constraints for CREST, Health Care Financing Administration (HCFA) reimbursement for hospital costs incurred by CREST patients will be essential. The involvement of academic scientists, industry, and three separate government agencies (NIH, FDA, HCFA) has presented many challenges in conducting the trial. A review of the pathways followed to meet these challenges may be helpful to others seeking to facilitate sharing of the costs and burdens of conducting innovative clinical research.</p> |
| first_indexed | 2024-12-13T12:13:32Z |
| format | Article |
| id | doaj.art-3fc653974032499c8e44ab74d08dce3e |
| institution | Directory Open Access Journal |
| issn | 1468-6708 |
| language | English |
| last_indexed | 2024-12-13T12:13:32Z |
| publishDate | 2001-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Current Controlled Trials in Cardiovascular Medicine |
| spelling | doaj.art-3fc653974032499c8e44ab74d08dce3e2022-12-21T23:46:46ZengBMCCurrent Controlled Trials in Cardiovascular Medicine1468-67082001-07-012416016410.1186/cvm-2-4-160Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and industry fundingBrott Thomas GHoward GeorgeHoward Virginia JHobson Robert WRoubin Gary SFerguson Robert DG<p>Abstract</p> <p>The Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) is a prospective, randomized, multicenter clinical trial of carotid endarterectomy (CEA) versus carotid artery stenting (CAS) as prevention for stroke in patients with symptomatic stenosis greater than or equal to 50%. CREST is sponsored by the US National Institute of Neurological Disorders and Stroke (NINDS) of the US National Institutes of Health (NIH), with additional support by a device manufacturer, and will provide data to the US Food and Drug Administration (FDA) for evaluation of a stent device. Because of budget constraints for CREST, Health Care Financing Administration (HCFA) reimbursement for hospital costs incurred by CREST patients will be essential. The involvement of academic scientists, industry, and three separate government agencies (NIH, FDA, HCFA) has presented many challenges in conducting the trial. A review of the pathways followed to meet these challenges may be helpful to others seeking to facilitate sharing of the costs and burdens of conducting innovative clinical research.</p>http://cvm.controlled-trials.com/content/2/4/160carotid endarterectomycarotid stentclinical trialgovernment agencies |
| spellingShingle | Brott Thomas G Howard George Howard Virginia J Hobson Robert W Roubin Gary S Ferguson Robert DG Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and industry funding Current Controlled Trials in Cardiovascular Medicine carotid endarterectomy carotid stent clinical trial government agencies |
| title | Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and industry funding |
| title_full | Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and industry funding |
| title_fullStr | Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and industry funding |
| title_full_unstemmed | Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and industry funding |
| title_short | Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and industry funding |
| title_sort | organizing the carotid revascularization endarterectomy versus stenting trial crest national institutes of health health care financing administration and industry funding |
| topic | carotid endarterectomy carotid stent clinical trial government agencies |
| url | http://cvm.controlled-trials.com/content/2/4/160 |
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