Dopamine induces platelet production from megakaryocytes via oxidative stress-mediated signaling pathways

Dopamine induces platelet production from megakaryocytes via oxidative stress-mediated signaling pathways

Dopamine (DA), a catecholamine neurotransmitter, is known to for its diverse roles on hematopoiesis, yet its function in thrombopoiesis remains poorly understood. This study shows that DA stimulation can directly induce platelet production from megakaryocytes (MKs) in the final stages of thrombopoie...

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Bibliographic Details
Main Authors: Shilei Chen, Mengjia Hu, Mingqiang Shen, Yang Xu, Cheng Wang, Xinmiao Wang, Fengju Li, Dongfeng Zeng, Fang Chen, Gaomei Zhao, Mo Chen, Fengchao Wang, Tianmin Cheng, Yongping Su, Jinghong Zhao, Song Wang, Junping Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2018-10-01
Series:Platelets
Subjects:
dopamine
megakaryocyte
oxidative stress
platelet
thrombopoiesis
Online Access:http://dx.doi.org/10.1080/09537104.2017.1356451

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