Predictive bioinformatics identifies novel regulators of proliferation in a cancer stem cell model
The cancer stem cell model postulates that tumors are hierarchically organized with a minor population, the cancer stem cells, exhibiting unlimited proliferative potential. These cells give rise to the bulk of tumor cells, which retain a limited ability to divide. Without successful targeting of can...
Main Authors: | Evan Fields, Jonathan D. Wren, Constantin Georgescu, John R. Daum, Gary J. Gorbsky |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-01-01
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Series: | Stem Cell Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506117302398 |
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