CZT Detectors-Based SPECT Imaging: How Detector and Collimator Arrangement Can Determine the Overall Performance of the Tomograph
A technical comparison is described between two SPECT systems, one dedicated to cardiovascular studies and one general-purpose, to evaluate the advantages and disadvantages of their use in an organ-specific clinical setting. The comparison was made between a dedicated cardiac SPECT (Alcyone, Discove...
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| Format: | Article |
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MDPI AG
2021-09-01
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| Series: | Electronics |
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| Online Access: | https://www.mdpi.com/2079-9292/10/18/2230 |
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| author | Maria Filomena Santarelli Anna Mori Michelangelo Bertasi Vincenzo Positano Alessia Gimelli Michele Scipioni Paolo Marzullo Luigi Landini |
| author_facet | Maria Filomena Santarelli Anna Mori Michelangelo Bertasi Vincenzo Positano Alessia Gimelli Michele Scipioni Paolo Marzullo Luigi Landini |
| author_sort | Maria Filomena Santarelli |
| collection | DOAJ |
| description | A technical comparison is described between two SPECT systems, one dedicated to cardiovascular studies and one general-purpose, to evaluate the advantages and disadvantages of their use in an organ-specific clinical setting. The comparison was made between a dedicated cardiac SPECT (Alcyone, Discovery NM 530c, GE Healthcare) scanner and a general-purpose one (Discovery NM/CT 670 CZT, GE Healthcare). The two scanners differ in terms of hardware, mainly in the arrangement of the detectors and collimators, which are the main components of SPECT. A standard NEMA phantom was used to characterize the energy resolution, spatial resolution, and sensitivity for the two systems. Then, using a custom-made cardiac phantom, more specific indices were computed to evaluate the quality of cardiac images, such as signal-to-background noise ratio (SBNR), tissue-background contrast-to-noise ratio (TBCNR), and uniformity. Finally, the same indices were computed for clinical images acquired with the two systems from 11 subjects. Alcyone showed superior performance for dedicated cardiac imaging; however, its excellent qualities are aimed only at the study of the heart and only at patients with a low body-mass index, unlike Discovery NM/CT 670 CZT, which can be used for every anatomic district area and for every type of patient. |
| first_indexed | 2024-03-10T07:44:19Z |
| format | Article |
| id | doaj.art-3fce25d77af34afcb2af8173262ab1c5 |
| institution | Directory Open Access Journal |
| issn | 2079-9292 |
| language | English |
| last_indexed | 2024-03-10T07:44:19Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Electronics |
| spelling | doaj.art-3fce25d77af34afcb2af8173262ab1c52023-11-22T12:47:50ZengMDPI AGElectronics2079-92922021-09-011018223010.3390/electronics10182230CZT Detectors-Based SPECT Imaging: How Detector and Collimator Arrangement Can Determine the Overall Performance of the TomographMaria Filomena Santarelli0Anna Mori1Michelangelo Bertasi2Vincenzo Positano3Alessia Gimelli4Michele Scipioni5Paolo Marzullo6Luigi Landini7CNR Institute of Clinical Physiology, 56124 Pisa, ItalyDipartimento di Ingegneria dell’Informazione (DII), Pisa University, 56126 Pisa, ItalyFondazione Toscana “G. Monasterio”, 54124 Pisa, ItalyFondazione Toscana “G. Monasterio”, 54124 Pisa, ItalyFondazione Toscana “G. Monasterio”, 54124 Pisa, ItalyAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medi cal School, Boston, MA 02114, USAFondazione Toscana “G. Monasterio”, 54124 Pisa, ItalyDipartimento di Ingegneria dell’Informazione (DII), Pisa University, 56126 Pisa, ItalyA technical comparison is described between two SPECT systems, one dedicated to cardiovascular studies and one general-purpose, to evaluate the advantages and disadvantages of their use in an organ-specific clinical setting. The comparison was made between a dedicated cardiac SPECT (Alcyone, Discovery NM 530c, GE Healthcare) scanner and a general-purpose one (Discovery NM/CT 670 CZT, GE Healthcare). The two scanners differ in terms of hardware, mainly in the arrangement of the detectors and collimators, which are the main components of SPECT. A standard NEMA phantom was used to characterize the energy resolution, spatial resolution, and sensitivity for the two systems. Then, using a custom-made cardiac phantom, more specific indices were computed to evaluate the quality of cardiac images, such as signal-to-background noise ratio (SBNR), tissue-background contrast-to-noise ratio (TBCNR), and uniformity. Finally, the same indices were computed for clinical images acquired with the two systems from 11 subjects. Alcyone showed superior performance for dedicated cardiac imaging; however, its excellent qualities are aimed only at the study of the heart and only at patients with a low body-mass index, unlike Discovery NM/CT 670 CZT, which can be used for every anatomic district area and for every type of patient.https://www.mdpi.com/2079-9292/10/18/2230single-photon emission computed tomography (SPECT)collimatordetectorcardiac imaging |
| spellingShingle | Maria Filomena Santarelli Anna Mori Michelangelo Bertasi Vincenzo Positano Alessia Gimelli Michele Scipioni Paolo Marzullo Luigi Landini CZT Detectors-Based SPECT Imaging: How Detector and Collimator Arrangement Can Determine the Overall Performance of the Tomograph Electronics single-photon emission computed tomography (SPECT) collimator detector cardiac imaging |
| title | CZT Detectors-Based SPECT Imaging: How Detector and Collimator Arrangement Can Determine the Overall Performance of the Tomograph |
| title_full | CZT Detectors-Based SPECT Imaging: How Detector and Collimator Arrangement Can Determine the Overall Performance of the Tomograph |
| title_fullStr | CZT Detectors-Based SPECT Imaging: How Detector and Collimator Arrangement Can Determine the Overall Performance of the Tomograph |
| title_full_unstemmed | CZT Detectors-Based SPECT Imaging: How Detector and Collimator Arrangement Can Determine the Overall Performance of the Tomograph |
| title_short | CZT Detectors-Based SPECT Imaging: How Detector and Collimator Arrangement Can Determine the Overall Performance of the Tomograph |
| title_sort | czt detectors based spect imaging how detector and collimator arrangement can determine the overall performance of the tomograph |
| topic | single-photon emission computed tomography (SPECT) collimator detector cardiac imaging |
| url | https://www.mdpi.com/2079-9292/10/18/2230 |
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