Synovial sarcoma: when epigenetic changes dictate tumour development

Synovial sarcoma: when epigenetic changes dictate tumour development

Synovial sarcoma is a highly aggressive soft tissue malignancy that often affects adolescents and young adults. It is associated with a unique chromosomal translocation that results in the formation and expression of the fusion gene SS18-SSX, which underlies its pathogenesis. Although SS18-SSX pro...

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Bibliographic Details
Main Authors: Nicolo Riggi, Luisa Cironi, Ivan Stamenkovic
Format: Article
Language:English
Published: SMW supporting association (Trägerverein Swiss Medical Weekly SMW) 2018-12-01
Series:Swiss Medical Weekly
Subjects:
Chromatin
Epigenetics
pathogenesis
SS18-SSX
synovial sarcoma
Online Access:https://www.smw.ch/index.php/smw/article/view/2544

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