Optimizing the use of nirmatrelvir/ritonavir in solid organ transplant recipients with COVID-19: A review of immunosuppressant adjustment strategies

Optimizing the use of nirmatrelvir/ritonavir in solid organ transplant recipients with COVID-19: A review of immunosuppressant adjustment strategies

The coronavirus disease 2019 (COVID-19) pandemic has caused a significant burden of morbidity and mortality worldwide, with solid organ transplant recipients (SOTRs) being particularly vulnerable. Nirmatrelvir and ritonavir have demonstrated the potential for reducing the risk of hospitalization and...

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Bibliographic Details
Main Authors: Yangming Tang, Yue Li, Turun Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
COVID-19/SARS-CoV-2
drug interaction
immunosuppressant
nirmatrelvir and ritonavir/Paxlovid
pharmacology
solid organ transplantation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1150341/full

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