Implementing gradual, hyperbolic tapering of long-acting injectable antipsychotics by prolonging the inter-dose interval: an modelling study
Gradual, hyperbolic tapering has been proposed as a method to reduce the risk of withdrawal effects and potential relapse of an underlying condition by minimising disruption of existing equilibria. We applied hyperbolic tapering principles in silico to long-acting aripiprazole to generate regimens f...
Main Authors: | James R. O’Neill, David M. Taylor, Mark A. Horowitz |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2023-09-01
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Series: | Therapeutic Advances in Psychopharmacology |
Online Access: | https://doi.org/10.1177/20451253231198463 |
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