MCC950 Ameliorates Acute Liver Injury Through Modulating Macrophage Polarization and Myeloid-Derived Suppressor Cells Function

MCC950 Ameliorates Acute Liver Injury Through Modulating Macrophage Polarization and Myeloid-Derived Suppressor Cells Function

Acute liver injury (ALI) raises high mortality rates due to a rapid pathological process. MCC950, a highly selective nod-like receptor family pyrin domain containing 3 (NLRP3) inhibitor, has already been reported to show strong hepatoprotective effects in many different liver diseases. In this study...

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Bibliographic Details
Main Authors: Wei Yan, Yingchun Shen, Jinny Huang, Ling Lu, Qian Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Medicine
Subjects:
MCC950
acute liver injury
macrophage polarization
myeloid-derived suppressor cells
treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.752223/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2021.752223/full

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