Infectious Diseases of the Upper Gastrointestinal Tract
Infectious diseases of the upper gastrointestinal tract are rare, but certain bacteria including Treponema pallidum and Mycobacterium tuberculosis may infect the esophagus, stomach, and duodenum even in an immunocompetent individual. Gastric syphilis is difficult to diagnose because it presents with...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Yong Chan Lee
2019-03-01
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| Series: | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
| Subjects: | |
| Online Access: | http://helicojournal.org/upload/pdf/kjhugr-2019-19-1-16.pdf |
| _version_ | 1818979438468005888 |
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| author | Min Roh Yang Won Min |
| author_facet | Min Roh Yang Won Min |
| author_sort | Min Roh |
| collection | DOAJ |
| description | Infectious diseases of the upper gastrointestinal tract are rare, but certain bacteria including Treponema pallidum and Mycobacterium tuberculosis may infect the esophagus, stomach, and duodenum even in an immunocompetent individual. Gastric syphilis is difficult to diagnose because it presents with non-specific symptoms and diverse endoscopic findings. Nevertheless, gastric syphilis should be considered in the differential diagnosis when a patient presents with chronic inflammatory gastric lesions such as multiple erosive/ulcerative lesions and stricture or with other evidence of syphilis. Histological evaluation and specific serological tests should be performed if syphilis is suspected. Esophageal and gastroduodenal tuberculosis also exhibits non-specific clinical manifestations. The diagnosis is confirmed by mucosal biopsy or aspiration cytology revealing the presence of caseating granulomata and/or acid-fast bacilli. Mycobacterial culture and polymerase chain reaction should be incorporated into routine diagnostic studies to improve the diagnostic sensitivity. The diagnosis of tuberculosis is occasionally confirmed indirectly by an excellent response of the patient to anti-tubercular therapy. |
| first_indexed | 2024-12-20T16:59:32Z |
| format | Article |
| id | doaj.art-3fd96851c5fa4957b84640afc6473f90 |
| institution | Directory Open Access Journal |
| issn | 1738-3331 |
| language | English |
| last_indexed | 2024-12-20T16:59:32Z |
| publishDate | 2019-03-01 |
| publisher | Yong Chan Lee |
| record_format | Article |
| series | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
| spelling | doaj.art-3fd96851c5fa4957b84640afc6473f902022-12-21T19:32:35ZengYong Chan LeeThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312019-03-01191162210.7704/kjhugr.2019.19.1.16552Infectious Diseases of the Upper Gastrointestinal TractMin Roh0Yang Won Min1Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaDepartment of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaInfectious diseases of the upper gastrointestinal tract are rare, but certain bacteria including Treponema pallidum and Mycobacterium tuberculosis may infect the esophagus, stomach, and duodenum even in an immunocompetent individual. Gastric syphilis is difficult to diagnose because it presents with non-specific symptoms and diverse endoscopic findings. Nevertheless, gastric syphilis should be considered in the differential diagnosis when a patient presents with chronic inflammatory gastric lesions such as multiple erosive/ulcerative lesions and stricture or with other evidence of syphilis. Histological evaluation and specific serological tests should be performed if syphilis is suspected. Esophageal and gastroduodenal tuberculosis also exhibits non-specific clinical manifestations. The diagnosis is confirmed by mucosal biopsy or aspiration cytology revealing the presence of caseating granulomata and/or acid-fast bacilli. Mycobacterial culture and polymerase chain reaction should be incorporated into routine diagnostic studies to improve the diagnostic sensitivity. The diagnosis of tuberculosis is occasionally confirmed indirectly by an excellent response of the patient to anti-tubercular therapy.http://helicojournal.org/upload/pdf/kjhugr-2019-19-1-16.pdfDuodenumEsophagusStomachSyphilisTuberculosis |
| spellingShingle | Min Roh Yang Won Min Infectious Diseases of the Upper Gastrointestinal Tract The Korean Journal of Helicobacter and Upper Gastrointestinal Research Duodenum Esophagus Stomach Syphilis Tuberculosis |
| title | Infectious Diseases of the Upper Gastrointestinal Tract |
| title_full | Infectious Diseases of the Upper Gastrointestinal Tract |
| title_fullStr | Infectious Diseases of the Upper Gastrointestinal Tract |
| title_full_unstemmed | Infectious Diseases of the Upper Gastrointestinal Tract |
| title_short | Infectious Diseases of the Upper Gastrointestinal Tract |
| title_sort | infectious diseases of the upper gastrointestinal tract |
| topic | Duodenum Esophagus Stomach Syphilis Tuberculosis |
| url | http://helicojournal.org/upload/pdf/kjhugr-2019-19-1-16.pdf |
| work_keys_str_mv | AT minroh infectiousdiseasesoftheuppergastrointestinaltract AT yangwonmin infectiousdiseasesoftheuppergastrointestinaltract |