Level of Osteotropic Elements in the Jaw Bones of Experimental Animals in Terms of the Impact of Xenobiotics
Pollution of the environment with heavy metals, pesticides, nitrates leads to an unceasing deterioration of the population’s health, in particular, the dental one. Excessive intake of salts of heavy metals and nitrites is accompanied by changes in calcium-phosphorus metabolism rates, indicating a di...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Ivano-Frankivsk National Medical University
2019-06-01
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| Series: | Galician Medical Journal |
| Subjects: | |
| Online Access: | https://ifnmujournal.com/gmj/article/view/1051 |
| _version_ | 1819063125645721600 |
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| author | Mariana Kaminska Mykola Rozhko Hanna Ersteniuk |
| author_facet | Mariana Kaminska Mykola Rozhko Hanna Ersteniuk |
| author_sort | Mariana Kaminska |
| collection | DOAJ |
| description | Pollution of the environment with heavy metals, pesticides, nitrates leads to an unceasing deterioration of the population’s health, in particular, the dental one. Excessive intake of salts of heavy metals and nitrites is accompanied by changes in calcium-phosphorus metabolism rates, indicating a disorder of metabolic processes in bone tissue. This necessitates the study of the level of osteotropic elements of the jaw bone tissue.
Materials and methods of research. In the experiment on 80 white outbred male rats, the effects of cadmium chloride, sodium nitrite and their combined action on the content of osteotropic elements in the jaw bone were studied. The control group consisted of 10 intact animals.
Results. It was determined that in the dynamics (1st, 14th, 28th days) of both cadmium-nitrite, nitrite and cadmium intoxication there was observed the accumulation of cadmium and decrease of calcium, copper, zinc levels in bone tissue of animal jaws compared to intact group.
Conclusions.The most significant changes in the level of osteotropic elements in the jaw bones are found in the combined effect of xenobiotics, which is important for understanding of the metabolic processes in the oral cavity. |
| first_indexed | 2024-12-21T15:09:42Z |
| format | Article |
| id | doaj.art-3fda032104554b54aa5b5d7267f4017d |
| institution | Directory Open Access Journal |
| issn | 2414-1518 |
| language | English |
| last_indexed | 2024-12-21T15:09:42Z |
| publishDate | 2019-06-01 |
| publisher | Ivano-Frankivsk National Medical University |
| record_format | Article |
| series | Galician Medical Journal |
| spelling | doaj.art-3fda032104554b54aa5b5d7267f4017d2022-12-21T18:59:19ZengIvano-Frankivsk National Medical UniversityGalician Medical Journal2414-15182019-06-0126210.21802/gmj.2019.2.131051Level of Osteotropic Elements in the Jaw Bones of Experimental Animals in Terms of the Impact of XenobioticsMariana Kaminska0Mykola Rozhko1Hanna Ersteniuk2Ivano-Frankivsk National Medical University, Ivano-FrankivskIvano-Frankivsk National Medical University, Ivano-FrankivskIvano-Frankivsk National Medical University, Ivano-FrankivskPollution of the environment with heavy metals, pesticides, nitrates leads to an unceasing deterioration of the population’s health, in particular, the dental one. Excessive intake of salts of heavy metals and nitrites is accompanied by changes in calcium-phosphorus metabolism rates, indicating a disorder of metabolic processes in bone tissue. This necessitates the study of the level of osteotropic elements of the jaw bone tissue. Materials and methods of research. In the experiment on 80 white outbred male rats, the effects of cadmium chloride, sodium nitrite and their combined action on the content of osteotropic elements in the jaw bone were studied. The control group consisted of 10 intact animals. Results. It was determined that in the dynamics (1st, 14th, 28th days) of both cadmium-nitrite, nitrite and cadmium intoxication there was observed the accumulation of cadmium and decrease of calcium, copper, zinc levels in bone tissue of animal jaws compared to intact group. Conclusions.The most significant changes in the level of osteotropic elements in the jaw bones are found in the combined effect of xenobiotics, which is important for understanding of the metabolic processes in the oral cavity.https://ifnmujournal.com/gmj/article/view/1051intact animalscadmium intoxicationnitrite intoxicationnitrite-cadmium intoxicationmacro- and microelementsbone tissue |
| spellingShingle | Mariana Kaminska Mykola Rozhko Hanna Ersteniuk Level of Osteotropic Elements in the Jaw Bones of Experimental Animals in Terms of the Impact of Xenobiotics Galician Medical Journal intact animals cadmium intoxication nitrite intoxication nitrite-cadmium intoxication macro- and microelements bone tissue |
| title | Level of Osteotropic Elements in the Jaw Bones of Experimental Animals in Terms of the Impact of Xenobiotics |
| title_full | Level of Osteotropic Elements in the Jaw Bones of Experimental Animals in Terms of the Impact of Xenobiotics |
| title_fullStr | Level of Osteotropic Elements in the Jaw Bones of Experimental Animals in Terms of the Impact of Xenobiotics |
| title_full_unstemmed | Level of Osteotropic Elements in the Jaw Bones of Experimental Animals in Terms of the Impact of Xenobiotics |
| title_short | Level of Osteotropic Elements in the Jaw Bones of Experimental Animals in Terms of the Impact of Xenobiotics |
| title_sort | level of osteotropic elements in the jaw bones of experimental animals in terms of the impact of xenobiotics |
| topic | intact animals cadmium intoxication nitrite intoxication nitrite-cadmium intoxication macro- and microelements bone tissue |
| url | https://ifnmujournal.com/gmj/article/view/1051 |
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