Effect of hormone replacement therapy on amyloid beta (Aβ) plaque density in the rhesus macaque amygdala

Effect of hormone replacement therapy on amyloid beta (Aβ) plaque density in the rhesus macaque amygdala

BackgroundAmyloid beta (Aβ) plaque density was examined in the amygdala of rhesus macaques, to elucidate the influence of age, diet and hormonal environment.MethodsLuminex technology was used to measure cerebrospinal fluid (CSF) concentrations of Aβ40 and Aβ42 across three decades, while immunohisto...

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Bibliographic Details
Main Authors: Maria-Luisa Appleman, Jeremy L. Thomas, Alison R. Weiss, Benjamin I. Nilaver, Rita Cervera-Juanes, Steven G. Kohama, Henryk F. Urbanski
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
aging
Alzheimer’s disease
amyloid plaques
hormone replacement therapy (HRT)
rhesus macaque
menopause
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1326747/full

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