Case report: Highly response to low-dose brachytherapy in recurrent retroperitoneal leiomyosarcoma with FANCD2 frameshift mutation: a unique case study
We report a case of recurrent retroperitoneal leiomyosarcoma in a male who achieved a rapid and robust but transient clinical response to low-dose iodine-125 brachytherapy. A FANCD2 frameshift mutation was detected by gene sequencing in the cancerous tissue.
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2024-04-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2024.1339955/full |
| _version_ | 1797226544622469120 |
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| author | Xiao li Liu Jinxin Zhao Xue min Di Guohui Cao Hongtao Zhang Juan Wang |
| author_facet | Xiao li Liu Jinxin Zhao Xue min Di Guohui Cao Hongtao Zhang Juan Wang |
| author_sort | Xiao li Liu |
| collection | DOAJ |
| description | We report a case of recurrent retroperitoneal leiomyosarcoma in a male who achieved a rapid and robust but transient clinical response to low-dose iodine-125 brachytherapy. A FANCD2 frameshift mutation was detected by gene sequencing in the cancerous tissue. |
| first_indexed | 2024-04-24T14:26:36Z |
| format | Article |
| id | doaj.art-3fdea64e7c89411e95e691b17728e13b |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-04-24T14:26:36Z |
| publishDate | 2024-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-3fdea64e7c89411e95e691b17728e13b2024-04-03T04:36:40ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2024-04-011410.3389/fonc.2024.13399551339955Case report: Highly response to low-dose brachytherapy in recurrent retroperitoneal leiomyosarcoma with FANCD2 frameshift mutation: a unique case studyXiao li LiuJinxin ZhaoXue min DiGuohui CaoHongtao ZhangJuan WangWe report a case of recurrent retroperitoneal leiomyosarcoma in a male who achieved a rapid and robust but transient clinical response to low-dose iodine-125 brachytherapy. A FANCD2 frameshift mutation was detected by gene sequencing in the cancerous tissue.https://www.frontiersin.org/articles/10.3389/fonc.2024.1339955/fullretroperitoneal leiomyosarcomaFANCD2brachytherapyradioactive iodine-125low dose |
| spellingShingle | Xiao li Liu Jinxin Zhao Xue min Di Guohui Cao Hongtao Zhang Juan Wang Case report: Highly response to low-dose brachytherapy in recurrent retroperitoneal leiomyosarcoma with FANCD2 frameshift mutation: a unique case study Frontiers in Oncology retroperitoneal leiomyosarcoma FANCD2 brachytherapy radioactive iodine-125 low dose |
| title | Case report: Highly response to low-dose brachytherapy in recurrent retroperitoneal leiomyosarcoma with FANCD2 frameshift mutation: a unique case study |
| title_full | Case report: Highly response to low-dose brachytherapy in recurrent retroperitoneal leiomyosarcoma with FANCD2 frameshift mutation: a unique case study |
| title_fullStr | Case report: Highly response to low-dose brachytherapy in recurrent retroperitoneal leiomyosarcoma with FANCD2 frameshift mutation: a unique case study |
| title_full_unstemmed | Case report: Highly response to low-dose brachytherapy in recurrent retroperitoneal leiomyosarcoma with FANCD2 frameshift mutation: a unique case study |
| title_short | Case report: Highly response to low-dose brachytherapy in recurrent retroperitoneal leiomyosarcoma with FANCD2 frameshift mutation: a unique case study |
| title_sort | case report highly response to low dose brachytherapy in recurrent retroperitoneal leiomyosarcoma with fancd2 frameshift mutation a unique case study |
| topic | retroperitoneal leiomyosarcoma FANCD2 brachytherapy radioactive iodine-125 low dose |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2024.1339955/full |
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