<i>Helicobacter pylori</i> Avoids the Critical Activation of NLRP3 Inflammasome-Mediated Production of Oncogenic Mature IL-1β in Human Immune Cells

<i>Helicobacter pylori</i> Avoids the Critical Activation of NLRP3 Inflammasome-Mediated Production of Oncogenic Mature IL-1β in Human Immune Cells

<i>Helicobacter pylori</i> persistently colonizes the human stomach, and is associated with inflammation-induced gastric cancer. Bacterial crosstalk with the host immune system produces various inflammatory mediators and subsequent reactions in the host, but not bacterial clearance. Inte...

Full description

Bibliographic Details
Main Authors: Suneesh Kumar Pachathundikandi, Nicole Blaser, Heiko Bruns, Steffen Backert
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
Inflammasome
NLRP3
<i>Helicobacter pylori</i>
Interleukin-1β
Online Access:https://www.mdpi.com/2072-6694/12/4/803

Similar Items

Similar Items