Molecular and Phylogenetic Characterisation of a Highly Divergent Novel Parvovirus (Psittaciform Chaphamaparvovirus 2) in Australian <i>Neophema</i> Parrots
Parvoviruses under the genus <i>Chaphamaparvovirus</i> (subfamily <i>Hamaparvovirinae</i>) are highly divergent and have recently been identified in many animals. However, the detection and characterisation of parvoviruses in psittacine birds are limited. Therefore, this stud...
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MDPI AG
2021-11-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/10/12/1559 |
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| author | Subir Sarker |
| author_facet | Subir Sarker |
| author_sort | Subir Sarker |
| collection | DOAJ |
| description | Parvoviruses under the genus <i>Chaphamaparvovirus</i> (subfamily <i>Hamaparvovirinae</i>) are highly divergent and have recently been identified in many animals. However, the detection and characterisation of parvoviruses in psittacine birds are limited. Therefore, this study reports a novel parvovirus, tentatively named psittaciform chaphamaparvovirus 2 (PsChPV-2) under the genus <i>Chaphamaparvovirus</i>, which was identified in Australian <i>Neophema</i> birds. The PsChPV-2 genome is 4371 bp in length and encompasses four predicted open-reading frames, including two major genes, a nonstructural replicase gene (NS1), and a structural capsid gene (VP1). The NS1 and VP1 genes showed the closest amino acid identities of 56.2% and 47.7%, respectively, with a recently sequenced psittaciform chaphamaparvovirus 1 from a rainbow lorikeet (<i>Trichoglossus moluccanus</i>). Subsequent phylogenetic analyses exhibited that the novel PsChPV-2 is most closely related to other <i>chaphamaparvoviruses</i> of avian origin and has the greatest sequence identity with PsChPV-1 (60.6%). Further systematic investigation is warranted to explore the diversity with many avian-associated parvoviruses likely to be discovered. |
| first_indexed | 2024-03-10T03:22:17Z |
| format | Article |
| id | doaj.art-3fdf693320954eb993cf68a783f67f75 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T03:22:17Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
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| series | Pathogens |
| spelling | doaj.art-3fdf693320954eb993cf68a783f67f752023-11-23T10:00:38ZengMDPI AGPathogens2076-08172021-11-011012155910.3390/pathogens10121559Molecular and Phylogenetic Characterisation of a Highly Divergent Novel Parvovirus (Psittaciform Chaphamaparvovirus 2) in Australian <i>Neophema</i> ParrotsSubir Sarker0Department of Physiology, Anatomy and Microbiology, School of Life Sciences, La Trobe University, Bundoora, VIC 3086, AustraliaParvoviruses under the genus <i>Chaphamaparvovirus</i> (subfamily <i>Hamaparvovirinae</i>) are highly divergent and have recently been identified in many animals. However, the detection and characterisation of parvoviruses in psittacine birds are limited. Therefore, this study reports a novel parvovirus, tentatively named psittaciform chaphamaparvovirus 2 (PsChPV-2) under the genus <i>Chaphamaparvovirus</i>, which was identified in Australian <i>Neophema</i> birds. The PsChPV-2 genome is 4371 bp in length and encompasses four predicted open-reading frames, including two major genes, a nonstructural replicase gene (NS1), and a structural capsid gene (VP1). The NS1 and VP1 genes showed the closest amino acid identities of 56.2% and 47.7%, respectively, with a recently sequenced psittaciform chaphamaparvovirus 1 from a rainbow lorikeet (<i>Trichoglossus moluccanus</i>). Subsequent phylogenetic analyses exhibited that the novel PsChPV-2 is most closely related to other <i>chaphamaparvoviruses</i> of avian origin and has the greatest sequence identity with PsChPV-1 (60.6%). Further systematic investigation is warranted to explore the diversity with many avian-associated parvoviruses likely to be discovered.https://www.mdpi.com/2076-0817/10/12/1559parvoviruschaphamaparvovirusphylogeneticsmetagenomicsevolution |
| spellingShingle | Subir Sarker Molecular and Phylogenetic Characterisation of a Highly Divergent Novel Parvovirus (Psittaciform Chaphamaparvovirus 2) in Australian <i>Neophema</i> Parrots Pathogens parvovirus chaphamaparvovirus phylogenetics metagenomics evolution |
| title | Molecular and Phylogenetic Characterisation of a Highly Divergent Novel Parvovirus (Psittaciform Chaphamaparvovirus 2) in Australian <i>Neophema</i> Parrots |
| title_full | Molecular and Phylogenetic Characterisation of a Highly Divergent Novel Parvovirus (Psittaciform Chaphamaparvovirus 2) in Australian <i>Neophema</i> Parrots |
| title_fullStr | Molecular and Phylogenetic Characterisation of a Highly Divergent Novel Parvovirus (Psittaciform Chaphamaparvovirus 2) in Australian <i>Neophema</i> Parrots |
| title_full_unstemmed | Molecular and Phylogenetic Characterisation of a Highly Divergent Novel Parvovirus (Psittaciform Chaphamaparvovirus 2) in Australian <i>Neophema</i> Parrots |
| title_short | Molecular and Phylogenetic Characterisation of a Highly Divergent Novel Parvovirus (Psittaciform Chaphamaparvovirus 2) in Australian <i>Neophema</i> Parrots |
| title_sort | molecular and phylogenetic characterisation of a highly divergent novel parvovirus psittaciform chaphamaparvovirus 2 in australian i neophema i parrots |
| topic | parvovirus chaphamaparvovirus phylogenetics metagenomics evolution |
| url | https://www.mdpi.com/2076-0817/10/12/1559 |
| work_keys_str_mv | AT subirsarker molecularandphylogeneticcharacterisationofahighlydivergentnovelparvoviruspsittaciformchaphamaparvovirus2inaustralianineophemaiparrots |