Opn5L1 is a retinal receptor that behaves as a reverse and self-regenerating photoreceptor
Opsins are G protein-coupled receptors which are activated by light-triggered retinal 11-cis-to-all-trans photoisomerization. Here, the authors report a vertebrate non-visual opsin (Opn5L1) that functions as a Gi-coupled retinal receptor, is deactivated by light and can thermally self-regenerate.
Bibliographic Details
Main Authors: |
Keita Sato,
Takahiro Yamashita,
Hideyo Ohuchi,
Atsuko Takeuchi,
Hitoshi Gotoh,
Katsuhiko Ono,
Misao Mizuno,
Yasuhisa Mizutani,
Sayuri Tomonari,
Kazumi Sakai,
Yasushi Imamoto,
Akimori Wada,
Yoshinori Shichida |
Format: | Article
|
Language: | English |
Published: |
Nature Portfolio
2018-03-01
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Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/s41467-018-03603-3
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