An investigation of a measles outbreak in Japan and Taiwan, China, March–May 2018
Objective: To investigate a measles outbreak that spread to Japan and Taiwan, China during March–May 2018, exploring the characteristics of the super-spreading event. Methods: A contact investigation of the index case and reconstruction of the epidemiological dynamics of measles transmission were c...
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| Format: | Article |
| Language: | English |
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World Health Organization Regional Office for the Western Pacific
2018-08-01
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| Series: | Western Pacific Surveillance and Response |
| Subjects: | |
| Online Access: | https://ojs.wpro.who.int/ojs/index.php/wpsar/article/view/634/837 |
| _version_ | 1830354765668679680 |
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| author | Kazuki Shimizu Ryo Kinoshita Keita Yoshii Andrei R. Akhmetzhanov Sungmok Jung Hyojung Lee Hiroshi Nishiura |
| author_facet | Kazuki Shimizu Ryo Kinoshita Keita Yoshii Andrei R. Akhmetzhanov Sungmok Jung Hyojung Lee Hiroshi Nishiura |
| author_sort | Kazuki Shimizu |
| collection | DOAJ |
| description | Objective: To investigate a measles outbreak that spread to Japan and Taiwan, China during March–May 2018, exploring the characteristics of the super-spreading event.
Methods: A contact investigation of the index case and reconstruction of the epidemiological dynamics of measles transmission were conducted. Employing a mathematical model, the effective reproduction number was estimated for each generation of cases.
Results and discussion: A single index case gave rise to a total of 38 secondary cases, 33 in Japan and five in Taiwan, China. Subsequent chains of transmission were observed in highly vaccinated populations in both Japan and Taiwan, China. The effective reproduction number of the second generation was >1 for both Japan and Taiwan, China. In Japan, the reproduction number was estimated to be <1 during the third generation. Vaccination of susceptible individuals is essential to prevent secondary and tertiary transmission events. |
| first_indexed | 2024-12-20T01:36:59Z |
| format | Article |
| id | doaj.art-3fe730528fc347e9a36f649d296c039a |
| institution | Directory Open Access Journal |
| issn | 2094-7321 2094-7313 |
| language | English |
| last_indexed | 2024-12-20T01:36:59Z |
| publishDate | 2018-08-01 |
| publisher | World Health Organization Regional Office for the Western Pacific |
| record_format | Article |
| series | Western Pacific Surveillance and Response |
| spelling | doaj.art-3fe730528fc347e9a36f649d296c039a2022-12-21T19:57:59ZengWorld Health Organization Regional Office for the Western PacificWestern Pacific Surveillance and Response2094-73212094-73132018-08-0193253110.5365/wpsar.2018.9.2.005An investigation of a measles outbreak in Japan and Taiwan, China, March–May 2018Kazuki Shimizu0Ryo Kinoshita1Keita Yoshii2Andrei R. Akhmetzhanov3Sungmok Jung4Hyojung Lee5Hiroshi Nishiura6Graduate School of Medicine, Hokkaido University.Graduate School of Medicine, Hokkaido University.Graduate School of Medicine, Hokkaido University.Graduate School of Medicine, Hokkaido University.Graduate School of Medicine, Hokkaido University.Graduate School of Medicine, Hokkaido University.Graduate School of Medicine, Hokkaido University.Objective: To investigate a measles outbreak that spread to Japan and Taiwan, China during March–May 2018, exploring the characteristics of the super-spreading event. Methods: A contact investigation of the index case and reconstruction of the epidemiological dynamics of measles transmission were conducted. Employing a mathematical model, the effective reproduction number was estimated for each generation of cases. Results and discussion: A single index case gave rise to a total of 38 secondary cases, 33 in Japan and five in Taiwan, China. Subsequent chains of transmission were observed in highly vaccinated populations in both Japan and Taiwan, China. The effective reproduction number of the second generation was >1 for both Japan and Taiwan, China. In Japan, the reproduction number was estimated to be <1 during the third generation. Vaccination of susceptible individuals is essential to prevent secondary and tertiary transmission events.https://ojs.wpro.who.int/ojs/index.php/wpsar/article/view/634/837outbreak investigationepidemicMorbillivirusbasic reproduction numberimportationsuperspreader |
| spellingShingle | Kazuki Shimizu Ryo Kinoshita Keita Yoshii Andrei R. Akhmetzhanov Sungmok Jung Hyojung Lee Hiroshi Nishiura An investigation of a measles outbreak in Japan and Taiwan, China, March–May 2018 Western Pacific Surveillance and Response outbreak investigation epidemic Morbillivirus basic reproduction number importation superspreader |
| title | An investigation of a measles outbreak in Japan and Taiwan, China, March–May 2018 |
| title_full | An investigation of a measles outbreak in Japan and Taiwan, China, March–May 2018 |
| title_fullStr | An investigation of a measles outbreak in Japan and Taiwan, China, March–May 2018 |
| title_full_unstemmed | An investigation of a measles outbreak in Japan and Taiwan, China, March–May 2018 |
| title_short | An investigation of a measles outbreak in Japan and Taiwan, China, March–May 2018 |
| title_sort | investigation of a measles outbreak in japan and taiwan china march may 2018 |
| topic | outbreak investigation epidemic Morbillivirus basic reproduction number importation superspreader |
| url | https://ojs.wpro.who.int/ojs/index.php/wpsar/article/view/634/837 |
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