Immune Cytolytic Activity and Strategies for Therapeutic Treatment

Immune Cytolytic Activity and Strategies for Therapeutic Treatment

Intratumoral immune cytolytic activity (CYT), calculated as the geometric mean of granzyme-A (GZMA) and perforin-1 (PRF1) expression, has emerged as a critical factor in cancer immunotherapy, with significant implications for patient prognosis and treatment outcomes. Immune checkpoint pathways, the...

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Bibliographic Details
Main Authors:	Stephanie Agioti, Apostolos Zaravinos
Format:	Article
Language:	English
Published:	MDPI AG 2024-03-01
Series:	International Journal of Molecular Sciences
Subjects:	cytolytic activity tumor-infiltrating lymphocytes gene expression profiling spatial analysis techniques immune checkpoint pathways tumor microenvironment
Online Access:	https://www.mdpi.com/1422-0067/25/7/3624

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