Globular Adiponectin Limits Microglia Pro-Inflammatory Phenotype through an AdipoR1/NF-κB Signaling Pathway

Globular Adiponectin Limits Microglia Pro-Inflammatory Phenotype through an AdipoR1/NF-κB Signaling Pathway

We recently reported that increased levels of Adiponectin (ApN) in the brain led to microglia phenotype and activation state regulation, thus reducing both global brain inflammation and depressive-like behaviors in mice. Apart from this, little is known on ApN molecular effects on microglia, althoug...

Bibliográfalaš dieđut
Váldodahkkit:	Sarah Nicolas, Julie Cazareth, Hadi Zarif, Alice Guyon, Catherine Heurteaux, Joëlle Chabry, Agnès Petit-Paitel
Materiálatiipa:	Artihkal
Giella:	English
Almmustuhtton:	Frontiers Media S.A. 2017-11-01
Ráidu:	Frontiers in Cellular Neuroscience
Fáttát:	microglia astrocytes brain neuroinflammation adipokines cytokines
Liŋkkat:	http://journal.frontiersin.org/article/10.3389/fncel.2017.00352/full

Geahča maid

Adiponectin suppresses amyloid-β oligomer (AβO)-induced inflammatory response of microglia via AdipoR1-AMPK-NF-κB signaling pathway
Dahkki: Min Jian, et al.
Almmustuhtton: (2019-05-01)

Interaction of Microglia and Astrocytes in the Neurovascular Unit
Dahkki: Li-rong Liu, et al.
Almmustuhtton: (2020-07-01)

Peptide discovery across the spectrum of neuroinflammation; microglia and astrocyte phenotypical targeting, mediation, and mechanistic understanding
Dahkki: Benjamin A. Benita, et al.
Almmustuhtton: (2024-11-01)

Age Associated Changes In Transcription Of Adiponectin, AdipoR1 And AdipoR2 Genes In Pancreas Of Rats
Dahkki: Marziyeh Feyzi, et al.
Almmustuhtton: (2020-09-01)

AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin
Dahkki: Mario Ruiz, et al.
Almmustuhtton: (2019-05-01)

Prevention and Treatment Strategies for Alzheimer’s Disease: Focusing on Microglia and Astrocytes in Neuroinflammation
Dahkki: Zhang S, et al.
Almmustuhtton: (2024-10-01)

Evidence that erythropoietin modulates neuroinflammation through differential action on neurons, astrocytes, and microglia
Dahkki: Wesley S Bond, et al.
Almmustuhtton: (2014-10-01)

Microglia and astrocyte dysfunction in parkinson's disease
Dahkki: Tae-In Kam, et al.
Almmustuhtton: (2020-10-01)

Paroxetine suppresses reactive microglia-mediated but not lipopolysaccharide-induced inflammatory responses in primary astrocytes
Dahkki: Xiong Zhang, et al.
Almmustuhtton: (2020-02-01)

Role of Microglia and Astrocytes in Alzheimer’s Disease: From Neuroinflammation to Ca<sup>2+</sup> Homeostasis Dysregulation
Dahkki: Giulia Di Benedetto, et al.
Almmustuhtton: (2022-09-01)

DICAM in the Extracellular Vesicles from Astrocytes Attenuates Microglia Activation and Neuroinflammation
Dahkki: Jin Han, et al.
Almmustuhtton: (2022-09-01)

Dimethyl fumarate attenuates reactive microglia and long-term memory deficits following systemic immune challenge
Dahkki: Hallel C. Paraiso, et al.
Almmustuhtton: (2018-03-01)

Phenotypic transition of microglia into astrocyte-like cells associated with disease onset in a model of inherited ALS
Dahkki: Emiliano eTrias, et al.
Almmustuhtton: (2013-12-01)

Adiponectin/AdipoR Research and Its Implications for Lifestyle-Related Diseases
Dahkki: Masato Iwabu, et al.
Almmustuhtton: (2019-08-01)

Globular Adiponectin Inhibits the Apoptosis of Mesenchymal Stem Cells Induced by Hypoxia and Serum Deprivation via the AdipoR1-Mediated Pathway
Dahkki: Xia-Qiu Tian, et al.
Almmustuhtton: (2016-02-01)

Adiponectin Ameliorates GMH-Induced Brain Injury by Regulating Microglia M1/M2 Polarization Via AdipoR1/APPL1/AMPK/PPARγ Signaling Pathway in Neonatal Rats
Dahkki: Ningbo Xu, et al.
Almmustuhtton: (2022-06-01)

Microglia–Astrocyte Interaction in Neural Development and Neural Pathogenesis
Dahkki: Meiqi Sun, et al.
Almmustuhtton: (2023-07-01)

Sequential Isolation of Microglia and Astrocytes from Young and Aged Adult Mouse Brains for Downstream Transcriptomic Analysis
Dahkki: Ruchelle G. Buenaventura, et al.
Almmustuhtton: (2022-09-01)

AdipoRon Engages Microglia to Antinociception through the AdipoR1/AMPK Pathway in SNI Mice
Dahkki: Qian Fang, et al.
Almmustuhtton: (2023-01-01)

Emerging role of non-coding RNAs in neuroinflammation mediated by microglia and astrocytes
Dahkki: Ruicheng Yang, et al.
Almmustuhtton: (2023-07-01)

Microglia and astrocytes underlie neuroinflammation and synaptic susceptibility in autism spectrum disorder
Dahkki: Yue Xiong, et al.
Almmustuhtton: (2023-03-01)

Affective Immunology: The Crosstalk Between Microglia and Astrocytes Plays Key Role?
Dahkki: Linglin Yang, et al.
Almmustuhtton: (2020-08-01)

AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice
Dahkki: Masato Iwabu, et al.
Almmustuhtton: (2021-01-01)

Phagocytic Activities of Reactive Microglia and Astrocytes Associated with Prion Diseases Are Dysregulated in Opposite Directions
Dahkki: Anshuman Sinha, et al.
Almmustuhtton: (2021-07-01)

Microglia-Dependent and Independent Brain Cytoprotective Effects of Mycophenolate Mofetil During Neuronal Damage
Dahkki: Joshua Kleine, et al.
Almmustuhtton: (2022-04-01)

Cottonseed oil alleviates ischemic stroke injury by inhibiting the inflammatory activation of microglia and astrocyte
Dahkki: Min Liu, et al.
Almmustuhtton: (2020-09-01)

Activation of NLRP3 Is Required for a Functional and Beneficial Microglia Response after Brain Trauma
Dahkki: Ana Belen Lopez-Rodriguez, et al.
Almmustuhtton: (2022-07-01)

Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease
Dahkki: Marta Vicente-Rodríguez, et al.
Almmustuhtton: (2023-04-01)

A primary neural cell culture model to study neuron, astrocyte, and microglia interactions in neuroinflammation
Dahkki: Noah Goshi, et al.
Almmustuhtton: (2020-05-01)

Human microglia and astrocytes constitutively express the neurokinin-1 receptor and functionally respond to substance P
Dahkki: Amanda R. Burmeister, et al.
Almmustuhtton: (2017-12-01)

Mechanisms and Emerging Regulators of Neuroinflammation: Exploring New Therapeutic Strategies for Neurological Disorders
Dahkki: Mi Eun Kim, et al.
Almmustuhtton: (2024-12-01)

Neuroinflammation in epileptogenesis: from pathophysiology to therapeutic strategies
Dahkki: Wenjun Li, et al.
Almmustuhtton: (2023-12-01)

Cathelicidin-Related Antimicrobial Peptide Negatively Regulates Bacterial Endotoxin-Induced Glial Activation
Dahkki: Anup Bhusal, et al.
Almmustuhtton: (2022-12-01)

Circadian cycle and neuroinflammation
Dahkki: Xu Xinzi, et al.
Almmustuhtton: (2023-10-01)

Valproic Acid Reduces Neuroinflammation to Provide Retinal Ganglion Cell Neuroprotection in the Retina Axotomy Model
Dahkki: James R. Tribble, et al.
Almmustuhtton: (2022-05-01)

Absence of BBSome function leads to astrocyte reactivity in the brain
Dahkki: Minati Singh, et al.
Almmustuhtton: (2019-05-01)

Astrocyte-Derived CCL2 is Associated with M1 Activation and Recruitment of Cultured Microglial Cells
Dahkki: Mingfeng He, et al.
Almmustuhtton: (2016-02-01)

Targeting neuroinflammation in Alzheimer’s disease
Dahkki: Bronzuoli MR, et al.
Almmustuhtton: (2016-11-01)

Dopamine receptor D3 signalling in astrocytes promotes neuroinflammation
Dahkki: Andro Montoya, et al.
Almmustuhtton: (2019-12-01)

Native adiponectin in serum binds to mammalian cells expressing T-cadherin, but not AdipoRs or calreticulin
Dahkki: Shunbun Kita, et al.
Almmustuhtton: (2019-10-01)