Globular Adiponectin Limits Microglia Pro-Inflammatory Phenotype through an AdipoR1/NF-κB Signaling Pathway

Globular Adiponectin Limits Microglia Pro-Inflammatory Phenotype through an AdipoR1/NF-κB Signaling Pathway

We recently reported that increased levels of Adiponectin (ApN) in the brain led to microglia phenotype and activation state regulation, thus reducing both global brain inflammation and depressive-like behaviors in mice. Apart from this, little is known on ApN molecular effects on microglia, althoug...

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Dades bibliogràfiques
Autors principals:	Sarah Nicolas, Julie Cazareth, Hadi Zarif, Alice Guyon, Catherine Heurteaux, Joëlle Chabry, Agnès Petit-Paitel
Format:	Article
Idioma:	English
Publicat:	Frontiers Media S.A. 2017-11-01
Col·lecció:	Frontiers in Cellular Neuroscience
Matèries:	microglia astrocytes brain neuroinflammation adipokines cytokines
Accés en línia:	http://journal.frontiersin.org/article/10.3389/fncel.2017.00352/full

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