Globular Adiponectin Limits Microglia Pro-Inflammatory Phenotype through an AdipoR1/NF-κB Signaling Pathway

Globular Adiponectin Limits Microglia Pro-Inflammatory Phenotype through an AdipoR1/NF-κB Signaling Pathway

We recently reported that increased levels of Adiponectin (ApN) in the brain led to microglia phenotype and activation state regulation, thus reducing both global brain inflammation and depressive-like behaviors in mice. Apart from this, little is known on ApN molecular effects on microglia, althoug...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Sarah Nicolas, Julie Cazareth, Hadi Zarif, Alice Guyon, Catherine Heurteaux, Joëlle Chabry, Agnès Petit-Paitel
Μορφή:	Άρθρο
Γλώσσα:	English
Έκδοση:	Frontiers Media S.A. 2017-11-01
Σειρά:	Frontiers in Cellular Neuroscience
Θέματα:	microglia astrocytes brain neuroinflammation adipokines cytokines
Διαθέσιμο Online:	http://journal.frontiersin.org/article/10.3389/fncel.2017.00352/full

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ανά: Li-rong Liu, κ.ά.
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ανά: Benjamin A. Benita, κ.ά.
Έκδοση: (2024-11-01)

Age Associated Changes In Transcription Of Adiponectin, AdipoR1 And AdipoR2 Genes In Pancreas Of Rats
ανά: Marziyeh Feyzi, κ.ά.
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AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin
ανά: Mario Ruiz, κ.ά.
Έκδοση: (2019-05-01)

Prevention and Treatment Strategies for Alzheimer’s Disease: Focusing on Microglia and Astrocytes in Neuroinflammation
ανά: Zhang S, κ.ά.
Έκδοση: (2024-10-01)

Evidence that erythropoietin modulates neuroinflammation through differential action on neurons, astrocytes, and microglia
ανά: Wesley S Bond, κ.ά.
Έκδοση: (2014-10-01)

Microglia and astrocyte dysfunction in parkinson's disease
ανά: Tae-In Kam, κ.ά.
Έκδοση: (2020-10-01)

Paroxetine suppresses reactive microglia-mediated but not lipopolysaccharide-induced inflammatory responses in primary astrocytes
ανά: Xiong Zhang, κ.ά.
Έκδοση: (2020-02-01)

Role of Microglia and Astrocytes in Alzheimer’s Disease: From Neuroinflammation to Ca<sup>2+</sup> Homeostasis Dysregulation
ανά: Giulia Di Benedetto, κ.ά.
Έκδοση: (2022-09-01)

DICAM in the Extracellular Vesicles from Astrocytes Attenuates Microglia Activation and Neuroinflammation
ανά: Jin Han, κ.ά.
Έκδοση: (2022-09-01)

Dimethyl fumarate attenuates reactive microglia and long-term memory deficits following systemic immune challenge
ανά: Hallel C. Paraiso, κ.ά.
Έκδοση: (2018-03-01)

Phenotypic transition of microglia into astrocyte-like cells associated with disease onset in a model of inherited ALS
ανά: Emiliano eTrias, κ.ά.
Έκδοση: (2013-12-01)

Adiponectin/AdipoR Research and Its Implications for Lifestyle-Related Diseases
ανά: Masato Iwabu, κ.ά.
Έκδοση: (2019-08-01)

Globular Adiponectin Inhibits the Apoptosis of Mesenchymal Stem Cells Induced by Hypoxia and Serum Deprivation via the AdipoR1-Mediated Pathway
ανά: Xia-Qiu Tian, κ.ά.
Έκδοση: (2016-02-01)

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ανά: Ningbo Xu, κ.ά.
Έκδοση: (2022-06-01)

Microglia–Astrocyte Interaction in Neural Development and Neural Pathogenesis
ανά: Meiqi Sun, κ.ά.
Έκδοση: (2023-07-01)

Sequential Isolation of Microglia and Astrocytes from Young and Aged Adult Mouse Brains for Downstream Transcriptomic Analysis
ανά: Ruchelle G. Buenaventura, κ.ά.
Έκδοση: (2022-09-01)

AdipoRon Engages Microglia to Antinociception through the AdipoR1/AMPK Pathway in SNI Mice
ανά: Qian Fang, κ.ά.
Έκδοση: (2023-01-01)

Emerging role of non-coding RNAs in neuroinflammation mediated by microglia and astrocytes
ανά: Ruicheng Yang, κ.ά.
Έκδοση: (2023-07-01)

Microglia and astrocytes underlie neuroinflammation and synaptic susceptibility in autism spectrum disorder
ανά: Yue Xiong, κ.ά.
Έκδοση: (2023-03-01)

Affective Immunology: The Crosstalk Between Microglia and Astrocytes Plays Key Role?
ανά: Linglin Yang, κ.ά.
Έκδοση: (2020-08-01)

AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice
ανά: Masato Iwabu, κ.ά.
Έκδοση: (2021-01-01)

Phagocytic Activities of Reactive Microglia and Astrocytes Associated with Prion Diseases Are Dysregulated in Opposite Directions
ανά: Anshuman Sinha, κ.ά.
Έκδοση: (2021-07-01)

Microglia-Dependent and Independent Brain Cytoprotective Effects of Mycophenolate Mofetil During Neuronal Damage
ανά: Joshua Kleine, κ.ά.
Έκδοση: (2022-04-01)

Cottonseed oil alleviates ischemic stroke injury by inhibiting the inflammatory activation of microglia and astrocyte
ανά: Min Liu, κ.ά.
Έκδοση: (2020-09-01)

Activation of NLRP3 Is Required for a Functional and Beneficial Microglia Response after Brain Trauma
ανά: Ana Belen Lopez-Rodriguez, κ.ά.
Έκδοση: (2022-07-01)

Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease
ανά: Marta Vicente-Rodríguez, κ.ά.
Έκδοση: (2023-04-01)

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ανά: Noah Goshi, κ.ά.
Έκδοση: (2020-05-01)

Human microglia and astrocytes constitutively express the neurokinin-1 receptor and functionally respond to substance P
ανά: Amanda R. Burmeister, κ.ά.
Έκδοση: (2017-12-01)

Mechanisms and Emerging Regulators of Neuroinflammation: Exploring New Therapeutic Strategies for Neurological Disorders
ανά: Mi Eun Kim, κ.ά.
Έκδοση: (2024-12-01)

Neuroinflammation in epileptogenesis: from pathophysiology to therapeutic strategies
ανά: Wenjun Li, κ.ά.
Έκδοση: (2023-12-01)

Cathelicidin-Related Antimicrobial Peptide Negatively Regulates Bacterial Endotoxin-Induced Glial Activation
ανά: Anup Bhusal, κ.ά.
Έκδοση: (2022-12-01)

Circadian cycle and neuroinflammation
ανά: Xu Xinzi, κ.ά.
Έκδοση: (2023-10-01)

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ανά: James R. Tribble, κ.ά.
Έκδοση: (2022-05-01)

Absence of BBSome function leads to astrocyte reactivity in the brain
ανά: Minati Singh, κ.ά.
Έκδοση: (2019-05-01)

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ανά: Mingfeng He, κ.ά.
Έκδοση: (2016-02-01)

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ανά: Bronzuoli MR, κ.ά.
Έκδοση: (2016-11-01)

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