Cetirizine-induced fixed drug eruption
Cetirizine, a piperazine-derivative second-generation antihistaminic, is used for a wide variety of disorders such as urticaria, eczema, and allergies. Adverse reactions due to this drug are usually rare, especially fixed drug eruption (FDE), a delayed cell-mediated hypersensitivity reaction, is sca...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Journal of Research in Pharmacy Practice |
| Subjects: | |
| Online Access: | http://www.jrpp.net/article.asp?issn=2319-9644;year=2018;volume=7;issue=2;spage=111;epage=114;aulast=Gopal |
| _version_ | 1811268350289903616 |
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| author | Srija Gopal Selvalaxmi Gnanasegaran Gerard Marshall Raj Sakthibalan Murugesan Mangaiarkkarasi Adhimoolam |
| author_facet | Srija Gopal Selvalaxmi Gnanasegaran Gerard Marshall Raj Sakthibalan Murugesan Mangaiarkkarasi Adhimoolam |
| author_sort | Srija Gopal |
| collection | DOAJ |
| description | Cetirizine, a piperazine-derivative second-generation antihistaminic, is used for a wide variety of disorders such as urticaria, eczema, and allergies. Adverse reactions due to this drug are usually rare, especially fixed drug eruption (FDE), a delayed cell-mediated hypersensitivity reaction, is scarce. Here, we report a case of cetirizine-induced FDE. A 34-year-old female developed hyperpigmented, itchy patches over both forearms, legs, feet, and right side of the chest after taking tablet cetirizine for dry cough with similar episode 2 years back on the same sites. The patient responded slowly with conservative treatment and the lesions disappeared after 10 days. She was advised to avoid the causative in near future. This case report highlighted FDE due to an antihistaminic which themselves will be prescribed to treat allergies. |
| first_indexed | 2024-04-12T21:21:17Z |
| format | Article |
| id | doaj.art-3fef441a506b45cdaee5491c8043bb5e |
| institution | Directory Open Access Journal |
| issn | 2319-9644 2279-042X |
| language | English |
| last_indexed | 2024-04-12T21:21:17Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Research in Pharmacy Practice |
| spelling | doaj.art-3fef441a506b45cdaee5491c8043bb5e2022-12-22T03:16:18ZengWolters Kluwer Medknow PublicationsJournal of Research in Pharmacy Practice2319-96442279-042X2018-01-017211111410.4103/jrpp.JRPP_17_99Cetirizine-induced fixed drug eruptionSrija GopalSelvalaxmi GnanasegaranGerard Marshall RajSakthibalan MurugesanMangaiarkkarasi AdhimoolamCetirizine, a piperazine-derivative second-generation antihistaminic, is used for a wide variety of disorders such as urticaria, eczema, and allergies. Adverse reactions due to this drug are usually rare, especially fixed drug eruption (FDE), a delayed cell-mediated hypersensitivity reaction, is scarce. Here, we report a case of cetirizine-induced FDE. A 34-year-old female developed hyperpigmented, itchy patches over both forearms, legs, feet, and right side of the chest after taking tablet cetirizine for dry cough with similar episode 2 years back on the same sites. The patient responded slowly with conservative treatment and the lesions disappeared after 10 days. She was advised to avoid the causative in near future. This case report highlighted FDE due to an antihistaminic which themselves will be prescribed to treat allergies.http://www.jrpp.net/article.asp?issn=2319-9644;year=2018;volume=7;issue=2;spage=111;epage=114;aulast=GopalCetirizinefixed drug eruptionhyperpigmented patches |
| spellingShingle | Srija Gopal Selvalaxmi Gnanasegaran Gerard Marshall Raj Sakthibalan Murugesan Mangaiarkkarasi Adhimoolam Cetirizine-induced fixed drug eruption Journal of Research in Pharmacy Practice Cetirizine fixed drug eruption hyperpigmented patches |
| title | Cetirizine-induced fixed drug eruption |
| title_full | Cetirizine-induced fixed drug eruption |
| title_fullStr | Cetirizine-induced fixed drug eruption |
| title_full_unstemmed | Cetirizine-induced fixed drug eruption |
| title_short | Cetirizine-induced fixed drug eruption |
| title_sort | cetirizine induced fixed drug eruption |
| topic | Cetirizine fixed drug eruption hyperpigmented patches |
| url | http://www.jrpp.net/article.asp?issn=2319-9644;year=2018;volume=7;issue=2;spage=111;epage=114;aulast=Gopal |
| work_keys_str_mv | AT srijagopal cetirizineinducedfixeddrugeruption AT selvalaxmignanasegaran cetirizineinducedfixeddrugeruption AT gerardmarshallraj cetirizineinducedfixeddrugeruption AT sakthibalanmurugesan cetirizineinducedfixeddrugeruption AT mangaiarkkarasiadhimoolam cetirizineinducedfixeddrugeruption |