Gold Nanoparticles With Special Shapes: Controlled Synthesis, Surface-enhanced Raman Scattering, and The Application in Biodetection

Specially shaped gold nanoparticles have intrigued considerable attention becausethey usually possess high-sensitivity surface-enhanced Raman scattering (SERS) and thusresult in large advantages in trace biodetermination. In this article, starch-capped goldnanoparticles with hexagon and boot shapes...

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Main Authors: Jinghong Li, Zhouping Wang, Jianqiang Hu
Format: Article
Language:English
Published: MDPI AG 2007-12-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/7/12/3299/
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author Jinghong Li
Zhouping Wang
Jianqiang Hu
author_facet Jinghong Li
Zhouping Wang
Jianqiang Hu
author_sort Jinghong Li
collection DOAJ
description Specially shaped gold nanoparticles have intrigued considerable attention becausethey usually possess high-sensitivity surface-enhanced Raman scattering (SERS) and thusresult in large advantages in trace biodetermination. In this article, starch-capped goldnanoparticles with hexagon and boot shapes were prepared through using a nontoxic andbiologically benign aqueous-phase synthetic route. Shape effects of gold nanoparticles onSERS properties were mainly investigated, and found that different-shaped goldnanoparticles possess different SERS properties. Especially, the boot-shaped nanoparticlescould induce more 100-fold SERS enhancements in sensitivity as compared with those fromgold nanospheres. The extremely strong SERS properties of gold nanoboots have beensuccessfully applied to the detection of avidin. The unique nanoboots with high-sensitivitySERS properties are also expected to find use in many other fields such as biolabel,bioassay, biodiagnosis, and even clinical diagnosis and therapy.
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spelling doaj.art-3fefd883f4d44480963ad3bcfec4b6ac2022-12-22T02:54:20ZengMDPI AGSensors1424-82202007-12-017123299331110.3390/s7123299Gold Nanoparticles With Special Shapes: Controlled Synthesis, Surface-enhanced Raman Scattering, and The Application in BiodetectionJinghong LiZhouping WangJianqiang HuSpecially shaped gold nanoparticles have intrigued considerable attention becausethey usually possess high-sensitivity surface-enhanced Raman scattering (SERS) and thusresult in large advantages in trace biodetermination. In this article, starch-capped goldnanoparticles with hexagon and boot shapes were prepared through using a nontoxic andbiologically benign aqueous-phase synthetic route. Shape effects of gold nanoparticles onSERS properties were mainly investigated, and found that different-shaped goldnanoparticles possess different SERS properties. Especially, the boot-shaped nanoparticlescould induce more 100-fold SERS enhancements in sensitivity as compared with those fromgold nanospheres. The extremely strong SERS properties of gold nanoboots have beensuccessfully applied to the detection of avidin. The unique nanoboots with high-sensitivitySERS properties are also expected to find use in many other fields such as biolabel,bioassay, biodiagnosis, and even clinical diagnosis and therapy.http://www.mdpi.com/1424-8220/7/12/3299/Gold nanoparticleSpecial shapeSurface-enhanced Raman scatteringBiodetection
spellingShingle Jinghong Li
Zhouping Wang
Jianqiang Hu
Gold Nanoparticles With Special Shapes: Controlled Synthesis, Surface-enhanced Raman Scattering, and The Application in Biodetection
Sensors
Gold nanoparticle
Special shape
Surface-enhanced Raman scattering
Biodetection
title Gold Nanoparticles With Special Shapes: Controlled Synthesis, Surface-enhanced Raman Scattering, and The Application in Biodetection
title_full Gold Nanoparticles With Special Shapes: Controlled Synthesis, Surface-enhanced Raman Scattering, and The Application in Biodetection
title_fullStr Gold Nanoparticles With Special Shapes: Controlled Synthesis, Surface-enhanced Raman Scattering, and The Application in Biodetection
title_full_unstemmed Gold Nanoparticles With Special Shapes: Controlled Synthesis, Surface-enhanced Raman Scattering, and The Application in Biodetection
title_short Gold Nanoparticles With Special Shapes: Controlled Synthesis, Surface-enhanced Raman Scattering, and The Application in Biodetection
title_sort gold nanoparticles with special shapes controlled synthesis surface enhanced raman scattering and the application in biodetection
topic Gold nanoparticle
Special shape
Surface-enhanced Raman scattering
Biodetection
url http://www.mdpi.com/1424-8220/7/12/3299/
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AT zhoupingwang goldnanoparticleswithspecialshapescontrolledsynthesissurfaceenhancedramanscatteringandtheapplicationinbiodetection
AT jianqianghu goldnanoparticleswithspecialshapescontrolledsynthesissurfaceenhancedramanscatteringandtheapplicationinbiodetection