Psoriasis and systemic lupus erythematosus in children – literature review based on case report

Immune-mediated inflammatory diseases are a group of diseases characterized by generalized inflammation that results from immune dysregulation, especially involving the mechanisms of acquired immunity. These diseases may be familial, showing that genetic factors play an important role in their devel...

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Main Authors: Izabela Dybowska-Gołota, Agnieszka Owczarczyk-Saczonek, Magdalena Krajewska-Włodarczyk, Zbigniew Żuber
Format: Article
Language:English
Published: Termedia Publishing House 2020-02-01
Series:Rheumatology
Subjects:
Online Access:https://www.termedia.pl/Psoriasis-and-systemic-lupus-erythematosus-in-children-literature-review-based-on-case-report,18,40059,1,1.html
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author Izabela Dybowska-Gołota
Agnieszka Owczarczyk-Saczonek
Magdalena Krajewska-Włodarczyk
Zbigniew Żuber
author_facet Izabela Dybowska-Gołota
Agnieszka Owczarczyk-Saczonek
Magdalena Krajewska-Włodarczyk
Zbigniew Żuber
author_sort Izabela Dybowska-Gołota
collection DOAJ
description Immune-mediated inflammatory diseases are a group of diseases characterized by generalized inflammation that results from immune dysregulation, especially involving the mechanisms of acquired immunity. These diseases may be familial, showing that genetic factors play an important role in their development. Additionally, the occurrence of one disease makes a patient prone to other diseases. However, the coexistence of systemic lupus erythematosus (SLE) and psoriasis (Ps) is very rare due to their distinct genetic determinants and mechanisms of pathogenesis. Treatment is also challenging, as medications used to treat one condition exacerbate or even trigger the symptoms of the other. This paper presents the case of a Ps patient with a family history of autoimmune diseases, who developed systemic lupus erythematosus during puberty, as well as a discussion on the coexistence of SLE and Ps in developmental age based on available literature searching for PubMed database and American College of Rheumatology and European League Against Rheumatism abstracts particularly in this subject.
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spelling doaj.art-3ff5685d24f7480cb1dcf7040c0997dc2022-12-21T22:59:30ZengTermedia Publishing HouseRheumatology0034-62332084-98342020-02-01581485510.5114/reum.2020.9351640059Psoriasis and systemic lupus erythematosus in children – literature review based on case reportIzabela Dybowska-GołotaAgnieszka Owczarczyk-SaczonekMagdalena Krajewska-WłodarczykZbigniew ŻuberImmune-mediated inflammatory diseases are a group of diseases characterized by generalized inflammation that results from immune dysregulation, especially involving the mechanisms of acquired immunity. These diseases may be familial, showing that genetic factors play an important role in their development. Additionally, the occurrence of one disease makes a patient prone to other diseases. However, the coexistence of systemic lupus erythematosus (SLE) and psoriasis (Ps) is very rare due to their distinct genetic determinants and mechanisms of pathogenesis. Treatment is also challenging, as medications used to treat one condition exacerbate or even trigger the symptoms of the other. This paper presents the case of a Ps patient with a family history of autoimmune diseases, who developed systemic lupus erythematosus during puberty, as well as a discussion on the coexistence of SLE and Ps in developmental age based on available literature searching for PubMed database and American College of Rheumatology and European League Against Rheumatism abstracts particularly in this subject.https://www.termedia.pl/Psoriasis-and-systemic-lupus-erythematosus-in-children-literature-review-based-on-case-report,18,40059,1,1.htmlpsoriasis systemic lupus erythematosus immune-mediated inflammatory diseases
spellingShingle Izabela Dybowska-Gołota
Agnieszka Owczarczyk-Saczonek
Magdalena Krajewska-Włodarczyk
Zbigniew Żuber
Psoriasis and systemic lupus erythematosus in children – literature review based on case report
Rheumatology
psoriasis
systemic lupus erythematosus
immune-mediated inflammatory diseases
title Psoriasis and systemic lupus erythematosus in children – literature review based on case report
title_full Psoriasis and systemic lupus erythematosus in children – literature review based on case report
title_fullStr Psoriasis and systemic lupus erythematosus in children – literature review based on case report
title_full_unstemmed Psoriasis and systemic lupus erythematosus in children – literature review based on case report
title_short Psoriasis and systemic lupus erythematosus in children – literature review based on case report
title_sort psoriasis and systemic lupus erythematosus in children literature review based on case report
topic psoriasis
systemic lupus erythematosus
immune-mediated inflammatory diseases
url https://www.termedia.pl/Psoriasis-and-systemic-lupus-erythematosus-in-children-literature-review-based-on-case-report,18,40059,1,1.html
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AT magdalenakrajewskawłodarczyk psoriasisandsystemiclupuserythematosusinchildrenliteraturereviewbasedoncasereport
AT zbigniewzuber psoriasisandsystemiclupuserythematosusinchildrenliteraturereviewbasedoncasereport