Angiopoietin-2 and the Vascular Endothelial Growth Factor Promote Migration and Invasion in Hepatocellular Carcinoma- and Intrahepatic Cholangiocarcinoma-Derived Spheroids

Angiopoietin-2 and the Vascular Endothelial Growth Factor Promote Migration and Invasion in Hepatocellular Carcinoma- and Intrahepatic Cholangiocarcinoma-Derived Spheroids

Aggressive hepatocellular carcinoma (HCC) overexpressing Angiopoietin-2 (ANG-2) (a protein linked with angiogenesis, proliferation, and epithelial–mesenchymal transition (EMT)), shares 95% of up-regulated genes and a similar poor prognosis with the proliferative subgroup of intrahepatic cholangiocar...

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Detalhes bibliográficos
Principais autores: Adriana Romanzi, Fabiola Milosa, Gemma Marcelli, Rosina Maria Critelli, Simone Lasagni, Isabella Gigante, Francesco Dituri, Filippo Schepis, Massimiliano Cadamuro, Gianluigi Giannelli, Luca Fabris, Erica Villa
Formato: Artigo
Idioma:English
Publicado em: MDPI AG 2023-12-01
coleção:Biomedicines
Assuntos:
proangiogenic factors
VEGF
Angiopoietin-2
3D cancer model
migration
invasiveness
Acesso em linha:https://www.mdpi.com/2227-9059/12/1/87

Internet

https://www.mdpi.com/2227-9059/12/1/87

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