Research progress and prospects of neoadjuvant endocrine therapy for breast cancer
Neoadjuvant endocrine therapy (NET) instead of neoadjuvant chemotherapy (NCT) is an effective clinical strategy for estrogen receptor (ER)-positive breast cancer patients, which can reduce tumor stage, achieve breast-conserving surgery for breast cancer and reduce the need for adjuvant chemotherapy....
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Format: | Article |
Language: | English |
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Editorial Office of China Oncology
2022-07-01
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Series: | Zhongguo aizheng zazhi |
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Online Access: | http://www.china-oncology.com/fileup/1007-3639/PDF/1660021600059-360286874.pdf |
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author | QIAN Yao, LIU Feng |
author_facet | QIAN Yao, LIU Feng |
author_sort | QIAN Yao, LIU Feng |
collection | DOAJ |
description | Neoadjuvant endocrine therapy (NET) instead of neoadjuvant chemotherapy (NCT) is an effective clinical strategy for estrogen receptor (ER)-positive breast cancer patients, which can reduce tumor stage, achieve breast-conserving surgery for breast cancer and reduce the need for adjuvant chemotherapy. This article aimed to review the latest research progress in several aeras: patient selection for NET, comparison of efficacy of NET, duration of NET, comparison and combined use of NET and NCT, NET combined with targeted therapy, window of opportunity trials, efficacy evaluation indicators and adjuvant therapy decision after neoadjuvant endocrine therapy. |
first_indexed | 2024-04-11T11:43:05Z |
format | Article |
id | doaj.art-3ffa793b807342a3842094bca9854b9e |
institution | Directory Open Access Journal |
issn | 1007-3639 |
language | English |
last_indexed | 2024-04-11T11:43:05Z |
publishDate | 2022-07-01 |
publisher | Editorial Office of China Oncology |
record_format | Article |
series | Zhongguo aizheng zazhi |
spelling | doaj.art-3ffa793b807342a3842094bca9854b9e2022-12-22T04:25:45ZengEditorial Office of China OncologyZhongguo aizheng zazhi1007-36392022-07-0132764364910.19401/j.cnki.1007-3639.2022.07.008Research progress and prospects of neoadjuvant endocrine therapy for breast cancerQIAN Yao, LIU Feng0Department of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin 150081, Heilongjiang Province, ChinaNeoadjuvant endocrine therapy (NET) instead of neoadjuvant chemotherapy (NCT) is an effective clinical strategy for estrogen receptor (ER)-positive breast cancer patients, which can reduce tumor stage, achieve breast-conserving surgery for breast cancer and reduce the need for adjuvant chemotherapy. This article aimed to review the latest research progress in several aeras: patient selection for NET, comparison of efficacy of NET, duration of NET, comparison and combined use of NET and NCT, NET combined with targeted therapy, window of opportunity trials, efficacy evaluation indicators and adjuvant therapy decision after neoadjuvant endocrine therapy.http://www.china-oncology.com/fileup/1007-3639/PDF/1660021600059-360286874.pdf|breast cancer|neoadjuvant endocrine therapy|prognosis |
spellingShingle | QIAN Yao, LIU Feng Research progress and prospects of neoadjuvant endocrine therapy for breast cancer Zhongguo aizheng zazhi |breast cancer|neoadjuvant endocrine therapy|prognosis |
title | Research progress and prospects of neoadjuvant endocrine therapy for breast cancer |
title_full | Research progress and prospects of neoadjuvant endocrine therapy for breast cancer |
title_fullStr | Research progress and prospects of neoadjuvant endocrine therapy for breast cancer |
title_full_unstemmed | Research progress and prospects of neoadjuvant endocrine therapy for breast cancer |
title_short | Research progress and prospects of neoadjuvant endocrine therapy for breast cancer |
title_sort | research progress and prospects of neoadjuvant endocrine therapy for breast cancer |
topic | |breast cancer|neoadjuvant endocrine therapy|prognosis |
url | http://www.china-oncology.com/fileup/1007-3639/PDF/1660021600059-360286874.pdf |
work_keys_str_mv | AT qianyaoliufeng researchprogressandprospectsofneoadjuvantendocrinetherapyforbreastcancer |