Traditional Uses, Origins, Chemistry and Pharmacology of Bombyx batryticatus: A Review
Bombyx batryticatus (B. batryticatus), a well-known traditional animal Chinese medicine, has been commonly used in China for thousands of years. The present paper reviewed advances in traditional uses, origin, chemical constituents, pharmacology and toxicity studies of B. batryticatus. The aim of th...
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MDPI AG
2017-10-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/22/10/1779 |
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| author | Meibian Hu Zhijie Yu Jiaolong Wang Wenxiang Fan Yujie Liu Jianghua Li He Xiao Yongchuan Li Wei Peng Chunjie Wu |
| author_facet | Meibian Hu Zhijie Yu Jiaolong Wang Wenxiang Fan Yujie Liu Jianghua Li He Xiao Yongchuan Li Wei Peng Chunjie Wu |
| author_sort | Meibian Hu |
| collection | DOAJ |
| description | Bombyx batryticatus (B. batryticatus), a well-known traditional animal Chinese medicine, has been commonly used in China for thousands of years. The present paper reviewed advances in traditional uses, origin, chemical constituents, pharmacology and toxicity studies of B. batryticatus. The aim of the paper is to provide more comprehensive references for modern B. batryticatus study and application. In Traditional Chinese Medicine (TCM) culture, drugs containing B. batryticatus have been used to treat convulsions, headaches, skin prurigo, scrofula, tonsillitis and fever. Many studies indicate B. batryticatus contains various compounds, including protein and peptides, fatty acids, flavonoids, nucleosides, steroids, coumarin, polysaccharide and others. Numerous investigations also have shown that extracts and compounds from B. batryticatus exert a wide spectrum of pharmacological effects both in vivo and in vitro, including effects on the nervous system, anticoagulant effects, antitumor effects, antibacterial and antifungal effects, antioxidant effects, hypoglycemic effects, as well as other effects. However, further studies should be undertaken to investigate bioactive compounds (especially proteins and peptides), toxic constituents, using forms and the quality evaluation and control of B. batryticatus. Furthermore, it will be interesting to study the mechanism of biological activities and structure-function relationships of bioactive constituents in B. batryticatus. |
| first_indexed | 2024-12-23T20:31:11Z |
| format | Article |
| id | doaj.art-3ffb298408dd4277be7f7063c0e734bb |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-23T20:31:11Z |
| publishDate | 2017-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-3ffb298408dd4277be7f7063c0e734bb2022-12-21T17:32:14ZengMDPI AGMolecules1420-30492017-10-012210177910.3390/molecules22101779molecules22101779Traditional Uses, Origins, Chemistry and Pharmacology of Bombyx batryticatus: A ReviewMeibian Hu0Zhijie Yu1Jiaolong Wang2Wenxiang Fan3Yujie Liu4Jianghua Li5He Xiao6Yongchuan Li7Wei Peng8Chunjie Wu9College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaCollege of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaCollege of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaCollege of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaCollege of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaCollege of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaChengdu Min-Jiang-Yuan Pharmaceutical Co., Ltd., Chengdu 611000, ChinaChengdu Min-Jiang-Yuan Pharmaceutical Co., Ltd., Chengdu 611000, ChinaCollege of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaCollege of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaBombyx batryticatus (B. batryticatus), a well-known traditional animal Chinese medicine, has been commonly used in China for thousands of years. The present paper reviewed advances in traditional uses, origin, chemical constituents, pharmacology and toxicity studies of B. batryticatus. The aim of the paper is to provide more comprehensive references for modern B. batryticatus study and application. In Traditional Chinese Medicine (TCM) culture, drugs containing B. batryticatus have been used to treat convulsions, headaches, skin prurigo, scrofula, tonsillitis and fever. Many studies indicate B. batryticatus contains various compounds, including protein and peptides, fatty acids, flavonoids, nucleosides, steroids, coumarin, polysaccharide and others. Numerous investigations also have shown that extracts and compounds from B. batryticatus exert a wide spectrum of pharmacological effects both in vivo and in vitro, including effects on the nervous system, anticoagulant effects, antitumor effects, antibacterial and antifungal effects, antioxidant effects, hypoglycemic effects, as well as other effects. However, further studies should be undertaken to investigate bioactive compounds (especially proteins and peptides), toxic constituents, using forms and the quality evaluation and control of B. batryticatus. Furthermore, it will be interesting to study the mechanism of biological activities and structure-function relationships of bioactive constituents in B. batryticatus.https://www.mdpi.com/1420-3049/22/10/1779Bombyx batryticatustraditional usesoriginchemical constituentspharmacologytoxicity |
| spellingShingle | Meibian Hu Zhijie Yu Jiaolong Wang Wenxiang Fan Yujie Liu Jianghua Li He Xiao Yongchuan Li Wei Peng Chunjie Wu Traditional Uses, Origins, Chemistry and Pharmacology of Bombyx batryticatus: A Review Molecules Bombyx batryticatus traditional uses origin chemical constituents pharmacology toxicity |
| title | Traditional Uses, Origins, Chemistry and Pharmacology of Bombyx batryticatus: A Review |
| title_full | Traditional Uses, Origins, Chemistry and Pharmacology of Bombyx batryticatus: A Review |
| title_fullStr | Traditional Uses, Origins, Chemistry and Pharmacology of Bombyx batryticatus: A Review |
| title_full_unstemmed | Traditional Uses, Origins, Chemistry and Pharmacology of Bombyx batryticatus: A Review |
| title_short | Traditional Uses, Origins, Chemistry and Pharmacology of Bombyx batryticatus: A Review |
| title_sort | traditional uses origins chemistry and pharmacology of bombyx batryticatus a review |
| topic | Bombyx batryticatus traditional uses origin chemical constituents pharmacology toxicity |
| url | https://www.mdpi.com/1420-3049/22/10/1779 |
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