Hypothyroidism among Children with Nephrotic Syndrome Admitted to a Tertiary Care Centre
Introduction: Nephrotic syndrome is a glomerular disease characterized by massive urinary protein loss occurring in children. Proteinuria also leads to loss of thyroid binding globulin affecting thyroid function. This study aimed to find out the prevalence of hypothyroidism among children with neph...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nepal Medical Association
2024-02-01
|
| Series: | Journal of Nepal Medical Association |
| Subjects: | |
| Online Access: | https://jnma.com.np/jnma/index.php/jnma/article/view/8455 |
| _version_ | 1797289585319870464 |
|---|---|
| author | Subhana Thapa Karki Najala Khatun Ram Hari Chapagain Nisha Jyoti Shrestha Sumit Agrawal |
| author_facet | Subhana Thapa Karki Najala Khatun Ram Hari Chapagain Nisha Jyoti Shrestha Sumit Agrawal |
| author_sort | Subhana Thapa Karki |
| collection | DOAJ |
| description |
Introduction: Nephrotic syndrome is a glomerular disease characterized by massive urinary protein loss occurring in children. Proteinuria also leads to loss of thyroid binding globulin affecting thyroid function. This study aimed to find out the prevalence of hypothyroidism among children with nephrotic syndrome admitted to a tertiary care centre.
Methods: A descriptive cross-sectional study was conducted among children with nephrotic syndrome admitted to a tertiary care centre from 06 July 2020 to 06 June 2021 after obtaining ethical approval from the Ethical Review Committee. They were tested for free T3, free T4 and TSH. A convenience sampling method was used. The point estimate was calculated at a 90% Confidence Interval.
Results: Among 69 children with nephrotic syndrome, the prevalence of hypothyroidism was 49 (71.01%) (62.03-80.00, 90% Confidence Interval).
Conclusions: The prevalence of hypothyroidism among children with nephrotic syndrome was higher than other studies done in similar settings.
|
| first_indexed | 2024-03-07T19:07:14Z |
| format | Article |
| id | doaj.art-3ffda684ee0d4bb8a1d39707d6542c95 |
| institution | Directory Open Access Journal |
| issn | 0028-2715 1815-672X |
| language | English |
| last_indexed | 2024-03-07T19:07:14Z |
| publishDate | 2024-02-01 |
| publisher | Nepal Medical Association |
| record_format | Article |
| series | Journal of Nepal Medical Association |
| spelling | doaj.art-3ffda684ee0d4bb8a1d39707d6542c952024-03-01T06:09:50ZengNepal Medical AssociationJournal of Nepal Medical Association0028-27151815-672X2024-02-016227010.31729/jnma.8455Hypothyroidism among Children with Nephrotic Syndrome Admitted to a Tertiary Care CentreSubhana Thapa Karki0Najala Khatun1Ram Hari Chapagain2Nisha Jyoti Shrestha3Sumit Agrawal4Department of Pediatric Medicine, Kanti Children’s Hospital, Maharajgunj, Kathmandu, NepalDepartment of Pediatric Medicine, National Academy of Medical Sciences, Mahaboudha, Kathmandu, NepalDepartment of Pediatric Medicine, National Academy of Medical Sciences, Mahaboudha, Kathmandu, NepalDepartment of Pediatric Medicine, National Academy of Medical Sciences, Mahaboudha, Kathmandu, NepalDepartment of Pediatric Medicine, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal Introduction: Nephrotic syndrome is a glomerular disease characterized by massive urinary protein loss occurring in children. Proteinuria also leads to loss of thyroid binding globulin affecting thyroid function. This study aimed to find out the prevalence of hypothyroidism among children with nephrotic syndrome admitted to a tertiary care centre. Methods: A descriptive cross-sectional study was conducted among children with nephrotic syndrome admitted to a tertiary care centre from 06 July 2020 to 06 June 2021 after obtaining ethical approval from the Ethical Review Committee. They were tested for free T3, free T4 and TSH. A convenience sampling method was used. The point estimate was calculated at a 90% Confidence Interval. Results: Among 69 children with nephrotic syndrome, the prevalence of hypothyroidism was 49 (71.01%) (62.03-80.00, 90% Confidence Interval). Conclusions: The prevalence of hypothyroidism among children with nephrotic syndrome was higher than other studies done in similar settings. https://jnma.com.np/jnma/index.php/jnma/article/view/8455childrenhypothyroidismnephrotic syndromeprevalence |
| spellingShingle | Subhana Thapa Karki Najala Khatun Ram Hari Chapagain Nisha Jyoti Shrestha Sumit Agrawal Hypothyroidism among Children with Nephrotic Syndrome Admitted to a Tertiary Care Centre Journal of Nepal Medical Association children hypothyroidism nephrotic syndrome prevalence |
| title | Hypothyroidism among Children with Nephrotic Syndrome Admitted to a Tertiary Care Centre |
| title_full | Hypothyroidism among Children with Nephrotic Syndrome Admitted to a Tertiary Care Centre |
| title_fullStr | Hypothyroidism among Children with Nephrotic Syndrome Admitted to a Tertiary Care Centre |
| title_full_unstemmed | Hypothyroidism among Children with Nephrotic Syndrome Admitted to a Tertiary Care Centre |
| title_short | Hypothyroidism among Children with Nephrotic Syndrome Admitted to a Tertiary Care Centre |
| title_sort | hypothyroidism among children with nephrotic syndrome admitted to a tertiary care centre |
| topic | children hypothyroidism nephrotic syndrome prevalence |
| url | https://jnma.com.np/jnma/index.php/jnma/article/view/8455 |
| work_keys_str_mv | AT subhanathapakarki hypothyroidismamongchildrenwithnephroticsyndromeadmittedtoatertiarycarecentre AT najalakhatun hypothyroidismamongchildrenwithnephroticsyndromeadmittedtoatertiarycarecentre AT ramharichapagain hypothyroidismamongchildrenwithnephroticsyndromeadmittedtoatertiarycarecentre AT nishajyotishrestha hypothyroidismamongchildrenwithnephroticsyndromeadmittedtoatertiarycarecentre AT sumitagrawal hypothyroidismamongchildrenwithnephroticsyndromeadmittedtoatertiarycarecentre |