Phosphatidylserine-microbubble targeting-activated microglia/macrophage in inflammation combined with ultrasound for breaking through the blood–brain barrier

Phosphatidylserine-microbubble targeting-activated microglia/macrophage in inflammation combined with ultrasound for breaking through the blood–brain barrier

Abstract Background and purpose Inflammatory reaction plays a crucial role in cerebral ischemia reperfusion (IR) injury. It has been shown that activated microglia long-term existed in cerebral ischemia and induced second injury. Therefore, we hypothesize that prepared phosphatidylserine (PS)-modifi...

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Bibliographic Details
Main Authors: Ranran Zhao, Jie Jiang, Huiwen Li, Min Chen, Renfa Liu, Sujuan Sun, De Ma, Xiaolong Liang, Shumin Wang
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Journal of Neuroinflammation
Subjects:
Ischemia
Blood–brain barrier
Ultrasound-targeted microbubble destruction
Microbubbles
Phosphatidylserine
Online Access:http://link.springer.com/article/10.1186/s12974-018-1368-1

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