Effect of Maternal Psoriasis on Pregnancy and Birth Outcomes: A Population-based Cohort Study from Denmark and Sweden

Studies on pregnancy and birth outcomes in women with psoriasis are scarce and the findings inconsistent. The effect of maternal psoriasis and its severity on the risk of adverse pregnancy and birth outcomes was examined. A cross-national population-based cohort study was performed using prospective...

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Main Authors: Gabriella Bröms, Ann Haerskjold, Fredrik Granath, Helle Kieler, Lars Pedersen, Ingegärd A. Berglind
Format: Article
Language:English
Published: Medical Journals Sweden 2018-06-01
Series:Acta Dermato-Venereologica
Subjects:
Online Access: https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2923
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author Gabriella Bröms
Ann Haerskjold
Fredrik Granath
Helle Kieler
Lars Pedersen
Ingegärd A. Berglind
author_facet Gabriella Bröms
Ann Haerskjold
Fredrik Granath
Helle Kieler
Lars Pedersen
Ingegärd A. Berglind
author_sort Gabriella Bröms
collection DOAJ
description Studies on pregnancy and birth outcomes in women with psoriasis are scarce and the findings inconsistent. The effect of maternal psoriasis and its severity on the risk of adverse pregnancy and birth outcomes was examined. A cross-national population-based cohort study was performed using prospectively collected data from Denmark and Sweden. Singleton births in women with psoriasis were identified in the national health registers between April 2007 and December 2012 and classified according to disease severity. Lifestyle factors, co-morbidity, pregnancy and birth outcomes were evaluated. A total of 8,097 births were identified in 6,103 women with psoriasis and 964 births in 753 women with psoriatic arthritis. Increased risk of gestational diabetes, gestational hypertension, pre-eclampsia, elective and emergency caesarean delivery was found in women with psoriasis. The risks were higher for women with severe psoriasis, who also had an increased risk of pre-term birth and low birth weight. Pre-conception counselling to improve maternal, pregnancy and birth outcome is encouraged.
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spelling doaj.art-4003dce71fae49fb8ae9e73ad93e40112022-12-22T04:05:45ZengMedical Journals SwedenActa Dermato-Venereologica0001-55551651-20572018-06-0198872873410.2340/00015555-29235195Effect of Maternal Psoriasis on Pregnancy and Birth Outcomes: A Population-based Cohort Study from Denmark and SwedenGabriella Bröms0Ann HaerskjoldFredrik GranathHelle KielerLars PedersenIngegärd A. Berglind Centre for Pharmacoepidemiology, Karolinska Institutet, SE-171 76 Stockholm, Sweden. Studies on pregnancy and birth outcomes in women with psoriasis are scarce and the findings inconsistent. The effect of maternal psoriasis and its severity on the risk of adverse pregnancy and birth outcomes was examined. A cross-national population-based cohort study was performed using prospectively collected data from Denmark and Sweden. Singleton births in women with psoriasis were identified in the national health registers between April 2007 and December 2012 and classified according to disease severity. Lifestyle factors, co-morbidity, pregnancy and birth outcomes were evaluated. A total of 8,097 births were identified in 6,103 women with psoriasis and 964 births in 753 women with psoriatic arthritis. Increased risk of gestational diabetes, gestational hypertension, pre-eclampsia, elective and emergency caesarean delivery was found in women with psoriasis. The risks were higher for women with severe psoriasis, who also had an increased risk of pre-term birth and low birth weight. Pre-conception counselling to improve maternal, pregnancy and birth outcome is encouraged. https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2923 psoriasisadversepregnancyandbirtheventsobservationalstudy
spellingShingle Gabriella Bröms
Ann Haerskjold
Fredrik Granath
Helle Kieler
Lars Pedersen
Ingegärd A. Berglind
Effect of Maternal Psoriasis on Pregnancy and Birth Outcomes: A Population-based Cohort Study from Denmark and Sweden
Acta Dermato-Venereologica
psoriasis
adversepregnancyandbirthevents
observationalstudy
title Effect of Maternal Psoriasis on Pregnancy and Birth Outcomes: A Population-based Cohort Study from Denmark and Sweden
title_full Effect of Maternal Psoriasis on Pregnancy and Birth Outcomes: A Population-based Cohort Study from Denmark and Sweden
title_fullStr Effect of Maternal Psoriasis on Pregnancy and Birth Outcomes: A Population-based Cohort Study from Denmark and Sweden
title_full_unstemmed Effect of Maternal Psoriasis on Pregnancy and Birth Outcomes: A Population-based Cohort Study from Denmark and Sweden
title_short Effect of Maternal Psoriasis on Pregnancy and Birth Outcomes: A Population-based Cohort Study from Denmark and Sweden
title_sort effect of maternal psoriasis on pregnancy and birth outcomes a population based cohort study from denmark and sweden
topic psoriasis
adversepregnancyandbirthevents
observationalstudy
url https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2923
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