Tachysterol2 increases the synthesis of fibroblast growth factor 23 in bone cells

Tachysterol2 increases the synthesis of fibroblast growth factor 23 in bone cells

Tachysterol2 (T2) is a photoisomer of the previtamin D2 found in UV-B-irradiated foods such as mushrooms or baker’s yeast. Due to its structural similarity to vitamin D, we hypothesized that T2 can affect vitamin D metabolism and in turn, fibroblast growth factor 23 (FGF23), a bone-derived phosphatu...

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Bibliographic Details
Main Authors: Franz Ewendt, Julia Kotwan, Stefan Ploch, Martina Feger, Frank Hirche, Michael Föller, Gabriele I. Stangl
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Nutrition
Subjects:
UV-B irradiation
food fortification
photoisomer
vitamin D receptor
calcium
phosphate
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.948264/full

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