Paraoxonase 2 attenuates macrophage triglyceride accumulation via inhibition of diacylglycerol acyltransferase 1

Paraoxonase 2 attenuates macrophage triglyceride accumulation via inhibition of diacylglycerol acyltransferase 1

This study questioned the role of paraoxonase 2 (PON2) in attenuation of macrophage lipids accumulation. Mouse peritoneal macrophages (MPMs) harvested from PON2-deficient mice versus control C57BL/6 mice, look like foam cells and were larger in size and filled with lipid droplets. Macrophage triglyc...

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Bibliographic Details
Main Authors:	Mira Rosenblat, Raymond Coleman, Srinivasa T. Reddy, Michael Aviram
Format:	Article
Language:	English
Published:	Elsevier 2009-05-01
Series:	Journal of Lipid Research
Subjects:	macrophages triglycerides oxidative stress
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520308397

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