Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer.

Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer.

Survivin is expressed in prostate cancer (PCa), and its downregulation sensitizes PCa cells to chemotherapeutic agents in vitro and in vivo. Small membrane-bound vesicles called exosomes, secreted from the endosomal membrane compartment, contain RNA and protein that they readily transport via exosom...

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Bibliographic Details
Main Authors: Salma Khan, Jessica M S Jutzy, Malyn May A Valenzuela, David Turay, Jonathan R Aspe, Arjun Ashok, Saied Mirshahidi, Dan Mercola, Michael B Lilly, Nathan R Wall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3473028?pdf=render

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