Potential role of miRNAs in age-related macular degeneration
A great number of miRNAs have been shown to play critical roles in pathological angiogenesis, the oxidative stress response, immune response and inflammation, all of which have been shown to have important roles in the pathogenesis and progression of age-related macular degeneration(AMD). Here we re...
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Format: | Article |
Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2015-01-01
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Series: | Guoji Yanke Zazhi |
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Online Access: | http://ies.ijo.cn/cn_publish/2015/1/201501017.pdf |
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author | Lin-Man Deng Hui Peng |
author_facet | Lin-Man Deng Hui Peng |
author_sort | Lin-Man Deng |
collection | DOAJ |
description | A great number of miRNAs have been shown to play critical roles in pathological angiogenesis, the oxidative stress response, immune response and inflammation, all of which have been shown to have important roles in the pathogenesis and progression of age-related macular degeneration(AMD). Here we reviewed the pathological processes involved in AMD and the roles of miRNAs in these processes, and discussed potential miRNAs-based therapeutics for AMD. |
first_indexed | 2024-12-18T08:23:14Z |
format | Article |
id | doaj.art-401512584f45473faf9d787169f780c9 |
institution | Directory Open Access Journal |
issn | 1672-5123 1672-5123 |
language | English |
last_indexed | 2024-12-18T08:23:14Z |
publishDate | 2015-01-01 |
publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
record_format | Article |
series | Guoji Yanke Zazhi |
spelling | doaj.art-401512584f45473faf9d787169f780c92022-12-21T21:14:42ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232015-01-01151616410.3980/j.issn.1672-5123.2015.1.17Potential role of miRNAs in age-related macular degenerationLin-Man Deng0Hui Peng1Department of Ophthalmology,the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, ChinaDepartment of Ophthalmology,the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, ChinaA great number of miRNAs have been shown to play critical roles in pathological angiogenesis, the oxidative stress response, immune response and inflammation, all of which have been shown to have important roles in the pathogenesis and progression of age-related macular degeneration(AMD). Here we reviewed the pathological processes involved in AMD and the roles of miRNAs in these processes, and discussed potential miRNAs-based therapeutics for AMD.http://ies.ijo.cn/cn_publish/2015/1/201501017.pdfmiRNAsage-related macular degenerationoxidative stressangiogenesisinflammation |
spellingShingle | Lin-Man Deng Hui Peng Potential role of miRNAs in age-related macular degeneration Guoji Yanke Zazhi miRNAs age-related macular degeneration oxidative stress angiogenesis inflammation |
title | Potential role of miRNAs in age-related macular degeneration |
title_full | Potential role of miRNAs in age-related macular degeneration |
title_fullStr | Potential role of miRNAs in age-related macular degeneration |
title_full_unstemmed | Potential role of miRNAs in age-related macular degeneration |
title_short | Potential role of miRNAs in age-related macular degeneration |
title_sort | potential role of mirnas in age related macular degeneration |
topic | miRNAs age-related macular degeneration oxidative stress angiogenesis inflammation |
url | http://ies.ijo.cn/cn_publish/2015/1/201501017.pdf |
work_keys_str_mv | AT linmandeng potentialroleofmirnasinagerelatedmaculardegeneration AT huipeng potentialroleofmirnasinagerelatedmaculardegeneration |