Potential role of miRNAs in age-related macular degeneration

A great number of miRNAs have been shown to play critical roles in pathological angiogenesis, the oxidative stress response, immune response and inflammation, all of which have been shown to have important roles in the pathogenesis and progression of age-related macular degeneration(AMD). Here we re...

Full description

Bibliographic Details
Main Authors: Lin-Man Deng, Hui Peng
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2015-01-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2015/1/201501017.pdf
_version_ 1818765761219395584
author Lin-Man Deng
Hui Peng
author_facet Lin-Man Deng
Hui Peng
author_sort Lin-Man Deng
collection DOAJ
description A great number of miRNAs have been shown to play critical roles in pathological angiogenesis, the oxidative stress response, immune response and inflammation, all of which have been shown to have important roles in the pathogenesis and progression of age-related macular degeneration(AMD). Here we reviewed the pathological processes involved in AMD and the roles of miRNAs in these processes, and discussed potential miRNAs-based therapeutics for AMD.
first_indexed 2024-12-18T08:23:14Z
format Article
id doaj.art-401512584f45473faf9d787169f780c9
institution Directory Open Access Journal
issn 1672-5123
1672-5123
language English
last_indexed 2024-12-18T08:23:14Z
publishDate 2015-01-01
publisher Press of International Journal of Ophthalmology (IJO PRESS)
record_format Article
series Guoji Yanke Zazhi
spelling doaj.art-401512584f45473faf9d787169f780c92022-12-21T21:14:42ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232015-01-01151616410.3980/j.issn.1672-5123.2015.1.17Potential role of miRNAs in age-related macular degenerationLin-Man Deng0Hui Peng1Department of Ophthalmology,the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, ChinaDepartment of Ophthalmology,the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, ChinaA great number of miRNAs have been shown to play critical roles in pathological angiogenesis, the oxidative stress response, immune response and inflammation, all of which have been shown to have important roles in the pathogenesis and progression of age-related macular degeneration(AMD). Here we reviewed the pathological processes involved in AMD and the roles of miRNAs in these processes, and discussed potential miRNAs-based therapeutics for AMD.http://ies.ijo.cn/cn_publish/2015/1/201501017.pdfmiRNAsage-related macular degenerationoxidative stressangiogenesisinflammation
spellingShingle Lin-Man Deng
Hui Peng
Potential role of miRNAs in age-related macular degeneration
Guoji Yanke Zazhi
miRNAs
age-related macular degeneration
oxidative stress
angiogenesis
inflammation
title Potential role of miRNAs in age-related macular degeneration
title_full Potential role of miRNAs in age-related macular degeneration
title_fullStr Potential role of miRNAs in age-related macular degeneration
title_full_unstemmed Potential role of miRNAs in age-related macular degeneration
title_short Potential role of miRNAs in age-related macular degeneration
title_sort potential role of mirnas in age related macular degeneration
topic miRNAs
age-related macular degeneration
oxidative stress
angiogenesis
inflammation
url http://ies.ijo.cn/cn_publish/2015/1/201501017.pdf
work_keys_str_mv AT linmandeng potentialroleofmirnasinagerelatedmaculardegeneration
AT huipeng potentialroleofmirnasinagerelatedmaculardegeneration