Childhood maltreatment and subsequent depressive symptoms: a prospective study of the sequential mediating role of self-esteem and internalizing/externalizing problems

Abstract Background Depression among adolescents is a seriously disabling public health problem with an extremely high prevalence. Identifying risk factors of depression at an early stage is important to reduce the disease burden. Childhood maltreatment (CM) is one of the major risk factors for depr...

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Main Authors: Wenyan Li, Wenjian Lai, Lan Guo, Wanxin Wang, Xiuwen Li, Liwan Zhu, Jingman Shi, Kayla M. Teopiz, Roger S. McIntyre, Ciyong Lu
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Psychiatry
Subjects:
Online Access:https://doi.org/10.1186/s12888-023-04654-7
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author Wenyan Li
Wenjian Lai
Lan Guo
Wanxin Wang
Xiuwen Li
Liwan Zhu
Jingman Shi
Kayla M. Teopiz
Roger S. McIntyre
Ciyong Lu
author_facet Wenyan Li
Wenjian Lai
Lan Guo
Wanxin Wang
Xiuwen Li
Liwan Zhu
Jingman Shi
Kayla M. Teopiz
Roger S. McIntyre
Ciyong Lu
author_sort Wenyan Li
collection DOAJ
description Abstract Background Depression among adolescents is a seriously disabling public health problem with an extremely high prevalence. Identifying risk factors of depression at an early stage is important to reduce the disease burden. Childhood maltreatment (CM) is one of the major risk factors for depression. The key mediating processes that how CM affects the development of depression, however, still need further clarification. The present study tested the mediating effect of self-esteem, internalizing problems, and externalizing problems between CM and depressive symptoms. Potential sex differences in the foregoing associations were also explored. Methods A three-wave longitudinal study was carried out among 1,957 middle and high school students from 69 classes in 10 public schools in the Guangdong province of China. Data collection started when students were in grades 7 and 10 (median age: 13.0, range: 11–18) between January and April 2019, and the students were followed up once a year thereafter. Self-reported CM, depressive symptoms, self-esteem, internalizing and externalizing problems, and other demographics were collected. The multiple serial mediation analysis was conducted. Results We found that CM was positively related to subsequent internalizing and externalizing problems, as well as depressive symptoms, while self-esteem was negatively related to depressive symptoms. Serial mediation analysis indicated that self-esteem (mediator 1) and internalizing problems (mediator 2) sequentially mediated the path from CM to depressive symptoms in the overall and male population. Moreover, with externalizing problems as mediator 2, self-esteem (mediator 1) acted as a partial mediator in the association between CM and depressive symptoms in males, whereas externalizing problems played a complete mediating role in females. Conclusion Findings revealed that self-esteem and internalizing problems sequentially mediated the influence of CM on depressive symptoms whereas externalizing problems played an independent mediating role. In addition, sex differences need to be taken into consideration when designing prevention and intervention strategies, given the different psychosocial processes between boys and girls.
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spelling doaj.art-4015be2451484862876aa77b358453632023-03-22T12:00:48ZengBMCBMC Psychiatry1471-244X2023-03-0123111410.1186/s12888-023-04654-7Childhood maltreatment and subsequent depressive symptoms: a prospective study of the sequential mediating role of self-esteem and internalizing/externalizing problemsWenyan Li0Wenjian Lai1Lan Guo2Wanxin Wang3Xiuwen Li4Liwan Zhu5Jingman Shi6Kayla M. Teopiz7Roger S. McIntyre8Ciyong Lu9Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen UniversityDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen UniversityDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen UniversityDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen UniversityDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen UniversityDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen UniversityDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen UniversityMood Disorders Psychopharmacology Unit, University Health NetworkMood Disorders Psychopharmacology Unit, University Health NetworkDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen UniversityAbstract Background Depression among adolescents is a seriously disabling public health problem with an extremely high prevalence. Identifying risk factors of depression at an early stage is important to reduce the disease burden. Childhood maltreatment (CM) is one of the major risk factors for depression. The key mediating processes that how CM affects the development of depression, however, still need further clarification. The present study tested the mediating effect of self-esteem, internalizing problems, and externalizing problems between CM and depressive symptoms. Potential sex differences in the foregoing associations were also explored. Methods A three-wave longitudinal study was carried out among 1,957 middle and high school students from 69 classes in 10 public schools in the Guangdong province of China. Data collection started when students were in grades 7 and 10 (median age: 13.0, range: 11–18) between January and April 2019, and the students were followed up once a year thereafter. Self-reported CM, depressive symptoms, self-esteem, internalizing and externalizing problems, and other demographics were collected. The multiple serial mediation analysis was conducted. Results We found that CM was positively related to subsequent internalizing and externalizing problems, as well as depressive symptoms, while self-esteem was negatively related to depressive symptoms. Serial mediation analysis indicated that self-esteem (mediator 1) and internalizing problems (mediator 2) sequentially mediated the path from CM to depressive symptoms in the overall and male population. Moreover, with externalizing problems as mediator 2, self-esteem (mediator 1) acted as a partial mediator in the association between CM and depressive symptoms in males, whereas externalizing problems played a complete mediating role in females. Conclusion Findings revealed that self-esteem and internalizing problems sequentially mediated the influence of CM on depressive symptoms whereas externalizing problems played an independent mediating role. In addition, sex differences need to be taken into consideration when designing prevention and intervention strategies, given the different psychosocial processes between boys and girls.https://doi.org/10.1186/s12888-023-04654-7Depressive symptomsChildhood maltreatmentSelf-esteemInternalizing and externalizing problemsSex differences
spellingShingle Wenyan Li
Wenjian Lai
Lan Guo
Wanxin Wang
Xiuwen Li
Liwan Zhu
Jingman Shi
Kayla M. Teopiz
Roger S. McIntyre
Ciyong Lu
Childhood maltreatment and subsequent depressive symptoms: a prospective study of the sequential mediating role of self-esteem and internalizing/externalizing problems
BMC Psychiatry
Depressive symptoms
Childhood maltreatment
Self-esteem
Internalizing and externalizing problems
Sex differences
title Childhood maltreatment and subsequent depressive symptoms: a prospective study of the sequential mediating role of self-esteem and internalizing/externalizing problems
title_full Childhood maltreatment and subsequent depressive symptoms: a prospective study of the sequential mediating role of self-esteem and internalizing/externalizing problems
title_fullStr Childhood maltreatment and subsequent depressive symptoms: a prospective study of the sequential mediating role of self-esteem and internalizing/externalizing problems
title_full_unstemmed Childhood maltreatment and subsequent depressive symptoms: a prospective study of the sequential mediating role of self-esteem and internalizing/externalizing problems
title_short Childhood maltreatment and subsequent depressive symptoms: a prospective study of the sequential mediating role of self-esteem and internalizing/externalizing problems
title_sort childhood maltreatment and subsequent depressive symptoms a prospective study of the sequential mediating role of self esteem and internalizing externalizing problems
topic Depressive symptoms
Childhood maltreatment
Self-esteem
Internalizing and externalizing problems
Sex differences
url https://doi.org/10.1186/s12888-023-04654-7
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