Concurrent nonavalent human papillomavirus (HPV) vaccination and immune stimulation with imiquimod to treat recalcitrant HPV-associated high grade vaginal intra-epithelial neoplasia

Concurrent nonavalent human papillomavirus (HPV) vaccination and immune stimulation with imiquimod to treat recalcitrant HPV-associated high grade vaginal intra-epithelial neoplasia

This is the first report describing detailed T cell responses to viral-like proteins contained in an HPV specific vaccine given in combination with Imiquimod for treatment of persistent VAIN2/3. We postulate that stimulation of the innate immune system with Imiquimod and the specific CD4 and CD8T ce...

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Bibliographic Details
Main Authors: R. Farrell, J. Zaunders, IM. Poynten, L. Anderson, L. Evans
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Gynecologic Oncology Reports
Subjects:
Human papillomavirus (HPV)
Vaginal intraepitheial neoplasia (VAIN)
Imiquimod
HPV vaccine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578924000298

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