Natural Rubber Films Incorporated with Red Propolis and Silver Nanoparticles Aimed for Occlusive Dressing Application
Abstract In this work, NRL films were enriched with red propolis and silver nanoparticles with the aim of obtaining dressings with bactericide properties. To improve the properties of these materials, plasma treatment was also applied to the films. Cytotoxic effects were evaluated by MTT and agar di...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Associação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímeros (ABPol)
2021-04-01
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| Series: | Materials Research |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392021000200228&tlng=en |
| _version_ | 1798021971333611520 |
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| author | Charlene Silvestrin Celi Garcia Ana Elisa Dotta Maddalozzo Paulo Miguel Celi Garcia Cristian Padilha Fontoura Melissa Machado Rodrigues Marcelo Giovanela João Antonio Pêgas Henriques Cesar Aguzzoli Janaina da Silva Crespo Mariana Roesch-Ely |
| author_facet | Charlene Silvestrin Celi Garcia Ana Elisa Dotta Maddalozzo Paulo Miguel Celi Garcia Cristian Padilha Fontoura Melissa Machado Rodrigues Marcelo Giovanela João Antonio Pêgas Henriques Cesar Aguzzoli Janaina da Silva Crespo Mariana Roesch-Ely |
| author_sort | Charlene Silvestrin Celi Garcia |
| collection | DOAJ |
| description | Abstract In this work, NRL films were enriched with red propolis and silver nanoparticles with the aim of obtaining dressings with bactericide properties. To improve the properties of these materials, plasma treatment was also applied to the films. Cytotoxic effects were evaluated by MTT and agar diffusion assays on secondary and stem cells. Determination of cell behavior on the films were assessed by EDS and FEG-SEM. In general, the plasma modified NRL films presented hydrophilic character, favorable condition for biomedical applications. RBS results showed that silver is probably in nanoparticulate form. MTT assays revealed that non-cytotoxic effects were observed for all the samples extracts. Either the plasma treatment or silver deposition were effective in sterilizing the samples and modifying their surfaces. It was demonstrated in this in vitro study that ADSCs associated with NRL films enriched with propolis should be considered promising for application in the healing of occlusive wounds. |
| first_indexed | 2024-04-11T17:22:10Z |
| format | Article |
| id | doaj.art-401dce29fd364efc808c439b9ad21def |
| institution | Directory Open Access Journal |
| issn | 1516-1439 |
| language | English |
| last_indexed | 2024-04-11T17:22:10Z |
| publishDate | 2021-04-01 |
| publisher | Associação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímeros (ABPol) |
| record_format | Article |
| series | Materials Research |
| spelling | doaj.art-401dce29fd364efc808c439b9ad21def2022-12-22T04:12:28ZengAssociação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímeros (ABPol)Materials Research1516-14392021-04-0124210.1590/1980-5373-mr-2020-0415Natural Rubber Films Incorporated with Red Propolis and Silver Nanoparticles Aimed for Occlusive Dressing ApplicationCharlene Silvestrin Celi GarciaAna Elisa Dotta MaddalozzoPaulo Miguel Celi GarciaCristian Padilha Fontourahttps://orcid.org/0000-0002-0700-1853Melissa Machado Rodrigueshttps://orcid.org/0000-0003-3299-572XMarcelo Giovanelahttps://orcid.org/0000-0003-0874-383XJoão Antonio Pêgas Henriqueshttps://orcid.org/0000-0002-5298-932XCesar AguzzoliJanaina da Silva Crespohttps://orcid.org/0000-0002-0935-242XMariana Roesch-Elyhttps://orcid.org/0000-0003-3339-1901Abstract In this work, NRL films were enriched with red propolis and silver nanoparticles with the aim of obtaining dressings with bactericide properties. To improve the properties of these materials, plasma treatment was also applied to the films. Cytotoxic effects were evaluated by MTT and agar diffusion assays on secondary and stem cells. Determination of cell behavior on the films were assessed by EDS and FEG-SEM. In general, the plasma modified NRL films presented hydrophilic character, favorable condition for biomedical applications. RBS results showed that silver is probably in nanoparticulate form. MTT assays revealed that non-cytotoxic effects were observed for all the samples extracts. Either the plasma treatment or silver deposition were effective in sterilizing the samples and modifying their surfaces. It was demonstrated in this in vitro study that ADSCs associated with NRL films enriched with propolis should be considered promising for application in the healing of occlusive wounds.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392021000200228&tlng=ennatural rubber latex filmsplasma treatmentwound dressingred propolissilver nanoparticles |
| spellingShingle | Charlene Silvestrin Celi Garcia Ana Elisa Dotta Maddalozzo Paulo Miguel Celi Garcia Cristian Padilha Fontoura Melissa Machado Rodrigues Marcelo Giovanela João Antonio Pêgas Henriques Cesar Aguzzoli Janaina da Silva Crespo Mariana Roesch-Ely Natural Rubber Films Incorporated with Red Propolis and Silver Nanoparticles Aimed for Occlusive Dressing Application Materials Research natural rubber latex films plasma treatment wound dressing red propolis silver nanoparticles |
| title | Natural Rubber Films Incorporated with Red Propolis and Silver Nanoparticles Aimed for Occlusive Dressing Application |
| title_full | Natural Rubber Films Incorporated with Red Propolis and Silver Nanoparticles Aimed for Occlusive Dressing Application |
| title_fullStr | Natural Rubber Films Incorporated with Red Propolis and Silver Nanoparticles Aimed for Occlusive Dressing Application |
| title_full_unstemmed | Natural Rubber Films Incorporated with Red Propolis and Silver Nanoparticles Aimed for Occlusive Dressing Application |
| title_short | Natural Rubber Films Incorporated with Red Propolis and Silver Nanoparticles Aimed for Occlusive Dressing Application |
| title_sort | natural rubber films incorporated with red propolis and silver nanoparticles aimed for occlusive dressing application |
| topic | natural rubber latex films plasma treatment wound dressing red propolis silver nanoparticles |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392021000200228&tlng=en |
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