Survey on iodine nutrition and thyroid function in adults in Xinjiang
BackgroundPrevious iodine nutrition monitoring has mainly focused on key populations such as pregnant women and children, and there are few reports on the status of iodine nutrition among adults in Xinjiang. ObjectiveTo understand the iodine nutrition and thyroid function status of healthy adults in...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Editorial Committee of Journal of Environmental and Occupational Medicine
2023-12-01
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| Series: | 环境与职业医学 |
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| Online Access: | http://www.jeom.org/article/cn/10.11836/JEOM23113 |
| _version_ | 1797232736986988544 |
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| author | ABUDUWAILI Gulinaize’er Li SUN Jia HUANG Yan MA |
| author_facet | ABUDUWAILI Gulinaize’er Li SUN Jia HUANG Yan MA |
| author_sort | ABUDUWAILI Gulinaize’er |
| collection | DOAJ |
| description | BackgroundPrevious iodine nutrition monitoring has mainly focused on key populations such as pregnant women and children, and there are few reports on the status of iodine nutrition among adults in Xinjiang. ObjectiveTo understand the iodine nutrition and thyroid function status of healthy adults in northern and southern Xinjiang, and to explore the effect of iodine nutrition level on thyroid function. MethodsIn May 2021, a stratified cluster sampling method was used to select one county (city) with good and one county (city) with poor economic conditions in each of the northern and southern regions of Xinjiang as the survey sites, and about 100 households were sampled from each survey site to collect samples of edible salt as well as random urine samples and fastingvenous blood of healthy adults aged 18 years or older. Urinary iodine was determined by cerium arsenide catalytic spectrophotometric method, salt iodine by direct titration method, and thyroid hormones by chemiluminescence immunoassay. Non-parametric test was used for comparison of non-normal quantitative data, t-test and analysis of variance were used for comparison of normal quantitative data, χ2 test was used for comparison of rates, and Spearman correlation analysis was used for correlation between salt iodine intake and urinary iodine level. ResultsA total of 436 salt samples were collected, the median salt iodine level was 28.18 mg·kg−1, and the coverage rate of qualified iodized salt was >90% in both northern and southern Xinjiang regions (P>0.05). A total of 436 adult urine samples were collected, the median urinary iodine was 219.73 μg·L−1. The urinary iodine medians of adults in the northern and southern regions were 209.47 μg·L−1 and 244.80 μg·L−1, respectively, and it was higher in the southern region than that in the northern region (P<0.05). The mean value and abnormality rate of serum free triiodothyronine (FT3) of adults in northern Xinjiang was lower than those in southern Xinjiang (P<0.05). The positive rates of anti-thyroglobulin antibody (TgAb) were 21.39% and 9.79%, the positive rates of anti-thyroid peroxidase antibody (TPOAb) were 27.36% and 10.64%, and the positive rates of both antibodies were 16.42% and 5.53% in the northern and southern regions, respectively. The positive rates of TgAb, TPOAb, and both antibodies in northern Xinjiang were higher than those in southern Xinjiang (P<0.05). The rates of abnormal thyroid function in northern Xinjiang and southern Xinjiang were 14.43% and 13.19%, respectively, with no statistically significant differences between the regions (P>0.05), in which subclinical hypothyroidism was predominant, with prevalence rates of 9.95% and 9.36% in the northern and southern regions, respectively. ConclusionSome adults in northern and southern Xinjiang have high iodine nutrition levels, and although no significant effect has been found on thyroid function in the population, the high iodine nutrition status still requires continuing concern. It is recommended to monitor the iodine nutritional status of adults continuously while strengthening health education for residents. |
| first_indexed | 2024-04-24T16:05:01Z |
| format | Article |
| id | doaj.art-401e2f62b8f34d38bc14cd13fc1c8181 |
| institution | Directory Open Access Journal |
| issn | 2095-9982 |
| language | English |
| last_indexed | 2024-04-24T16:05:01Z |
| publishDate | 2023-12-01 |
| publisher | Editorial Committee of Journal of Environmental and Occupational Medicine |
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| series | 环境与职业医学 |
| spelling | doaj.art-401e2f62b8f34d38bc14cd13fc1c81812024-04-01T05:48:14ZengEditorial Committee of Journal of Environmental and Occupational Medicine环境与职业医学2095-99822023-12-0140121419142310.11836/JEOM2311323113Survey on iodine nutrition and thyroid function in adults in XinjiangABUDUWAILI Gulinaize’er0Li SUN1Jia HUANG2Yan MA3School of Public Health, Xinjiang Medical University, Urumqi, Xinjiang 830011, ChinaYengisar County Center for Disease Control and Prevention, Kashgar, Xinjiang 844500, ChinaDepartment of Infectious Disease Prevention and Control, Xinjiang Uyghur Autonomous Region Centre for Disease Control and Prevention, Urumqi, Xinjiang 830002, ChinaSchool of Public Health, Xinjiang Medical University, Urumqi, Xinjiang 830011, ChinaBackgroundPrevious iodine nutrition monitoring has mainly focused on key populations such as pregnant women and children, and there are few reports on the status of iodine nutrition among adults in Xinjiang. ObjectiveTo understand the iodine nutrition and thyroid function status of healthy adults in northern and southern Xinjiang, and to explore the effect of iodine nutrition level on thyroid function. MethodsIn May 2021, a stratified cluster sampling method was used to select one county (city) with good and one county (city) with poor economic conditions in each of the northern and southern regions of Xinjiang as the survey sites, and about 100 households were sampled from each survey site to collect samples of edible salt as well as random urine samples and fastingvenous blood of healthy adults aged 18 years or older. Urinary iodine was determined by cerium arsenide catalytic spectrophotometric method, salt iodine by direct titration method, and thyroid hormones by chemiluminescence immunoassay. Non-parametric test was used for comparison of non-normal quantitative data, t-test and analysis of variance were used for comparison of normal quantitative data, χ2 test was used for comparison of rates, and Spearman correlation analysis was used for correlation between salt iodine intake and urinary iodine level. ResultsA total of 436 salt samples were collected, the median salt iodine level was 28.18 mg·kg−1, and the coverage rate of qualified iodized salt was >90% in both northern and southern Xinjiang regions (P>0.05). A total of 436 adult urine samples were collected, the median urinary iodine was 219.73 μg·L−1. The urinary iodine medians of adults in the northern and southern regions were 209.47 μg·L−1 and 244.80 μg·L−1, respectively, and it was higher in the southern region than that in the northern region (P<0.05). The mean value and abnormality rate of serum free triiodothyronine (FT3) of adults in northern Xinjiang was lower than those in southern Xinjiang (P<0.05). The positive rates of anti-thyroglobulin antibody (TgAb) were 21.39% and 9.79%, the positive rates of anti-thyroid peroxidase antibody (TPOAb) were 27.36% and 10.64%, and the positive rates of both antibodies were 16.42% and 5.53% in the northern and southern regions, respectively. The positive rates of TgAb, TPOAb, and both antibodies in northern Xinjiang were higher than those in southern Xinjiang (P<0.05). The rates of abnormal thyroid function in northern Xinjiang and southern Xinjiang were 14.43% and 13.19%, respectively, with no statistically significant differences between the regions (P>0.05), in which subclinical hypothyroidism was predominant, with prevalence rates of 9.95% and 9.36% in the northern and southern regions, respectively. ConclusionSome adults in northern and southern Xinjiang have high iodine nutrition levels, and although no significant effect has been found on thyroid function in the population, the high iodine nutrition status still requires continuing concern. It is recommended to monitor the iodine nutritional status of adults continuously while strengthening health education for residents.http://www.jeom.org/article/cn/10.11836/JEOM23113adultiodine nutritionurinary iodinesalt iodinethyroid function |
| spellingShingle | ABUDUWAILI Gulinaize’er Li SUN Jia HUANG Yan MA Survey on iodine nutrition and thyroid function in adults in Xinjiang 环境与职业医学 adult iodine nutrition urinary iodine salt iodine thyroid function |
| title | Survey on iodine nutrition and thyroid function in adults in Xinjiang |
| title_full | Survey on iodine nutrition and thyroid function in adults in Xinjiang |
| title_fullStr | Survey on iodine nutrition and thyroid function in adults in Xinjiang |
| title_full_unstemmed | Survey on iodine nutrition and thyroid function in adults in Xinjiang |
| title_short | Survey on iodine nutrition and thyroid function in adults in Xinjiang |
| title_sort | survey on iodine nutrition and thyroid function in adults in xinjiang |
| topic | adult iodine nutrition urinary iodine salt iodine thyroid function |
| url | http://www.jeom.org/article/cn/10.11836/JEOM23113 |
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