miR-145a-5p/Plexin-A2 promotes the migration of OECs and transplantation of miR-145a-5p engineered OECs enhances the functional recovery in rats with SCI

miR-145a-5p/Plexin-A2 promotes the migration of OECs and transplantation of miR-145a-5p engineered OECs enhances the functional recovery in rats with SCI

Background: Olfactory ensheathing cells (OECs) serve as a bridge by migrating at the site of spinal cord injury (SCI) to facilitate the repair of the neural structure and neural function. However, OEC migration at the injury site not only faces the complex and disordered internal environment but als...

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Bibliographic Details
Main Authors: MinChao Zhao, Jiaxi Li, Zhengchao Gao, Dong Guo, Yubing Yang, Fang Wang, Lumin Wang, Yang Yang, Xijing He, Haopeng Li, Su’e Chang
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Neurobiology of Disease
Subjects:
miR-145a-5p
Plexin-A2
OECs
Migration
Nerve repair
Spinal cord injury
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996123001432

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