Occupational Exposures and Cardiac Structure and Function: ECHO‐SOL (Echocardiographic Study of Latinos)
Background Our objective was to determine associations of occupational exposures with cardiac structure and function in Hispanic/Latino adults. Methods and Results Employed participants were included (n=782; 52% women, mean age 52.9 years). Occupational exposures to burning wood, vehicle exhaust, so...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-09-01
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| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| Subjects: | |
| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.120.016122 |
| _version_ | 1819175150200815616 |
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| author | Melissa S. Burroughs Peña Jean Claude Uwamungu Catherine M. Bulka Katrina Swett Krista M. Perreira Mayank M. Kansal Matthew Shane Loop Barry E. Hurwitz Martha Daviglus Carlos J. Rodriguez |
| author_facet | Melissa S. Burroughs Peña Jean Claude Uwamungu Catherine M. Bulka Katrina Swett Krista M. Perreira Mayank M. Kansal Matthew Shane Loop Barry E. Hurwitz Martha Daviglus Carlos J. Rodriguez |
| author_sort | Melissa S. Burroughs Peña |
| collection | DOAJ |
| description | Background Our objective was to determine associations of occupational exposures with cardiac structure and function in Hispanic/Latino adults. Methods and Results Employed participants were included (n=782; 52% women, mean age 52.9 years). Occupational exposures to burning wood, vehicle exhaust, solvents, pesticides, and metals at the current and longest‐held job were assessed by questionnaire. Survey multivariable linear regression analyses were used to model the relationship of each self‐reported exposure with echocardiographic measures of cardiac structure and function. Exposure to burning wood at the current job was associated with decreased left ventricular (LV) ejection fraction (−3.1%; standard error [SE], 1.0 [P=0.002]). When the analysis was restricted to exposure at the longest‐held job, occupational exposure to burning wood was associated with increased LV diastolic volume (6.7 mL; SE, 1.6 [P<0.0001]), decreased LV ejection fraction (−2.7%; SE, 0.6 [P<0.0001]), worse LV global longitudinal strain (1.0%; SE, 0.3 [P=0.0009]), and decreased right ventricular fractional area change (−0.02; SE, 0.004 [P<0.001]). Exposure to pesticides was associated with worse average global longitudinal strain (0.8%; SE, 0.2 [P<0.0001]). Exposure to metals was associated with worse global longitudinal strain in the 2‐chamber view (1.0%; SE, 0.5 [P=0.04]), increased stroke volume (3.6 mL; SE, 1.6 [P=0.03]), and increased LV mass indexed to BSA (9.2 g/m2; SE, 3.8 [P=0.01]) or height (4.4 g/m2.7; SE, 1.9 [P=0.02]). Conclusions Occupational exposures to burning wood, vehicle exhaust, pesticides, and metals were associated with abnormal parameters of LV and right ventricular systolic function. Reducing exposures to toxic chemicals and particulates in the workplace is a potential opportunity to prevent cardiovascular disease in populations at risk. |
| first_indexed | 2024-12-22T20:50:17Z |
| format | Article |
| id | doaj.art-401fd7a56bb1455aba0b4bac756a8e6f |
| institution | Directory Open Access Journal |
| issn | 2047-9980 |
| language | English |
| last_indexed | 2024-12-22T20:50:17Z |
| publishDate | 2020-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| spelling | doaj.art-401fd7a56bb1455aba0b4bac756a8e6f2022-12-21T18:13:07ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802020-09-0191710.1161/JAHA.120.016122Occupational Exposures and Cardiac Structure and Function: ECHO‐SOL (Echocardiographic Study of Latinos)Melissa S. Burroughs Peña0Jean Claude Uwamungu1Catherine M. Bulka2Katrina Swett3Krista M. Perreira4Mayank M. Kansal5Matthew Shane Loop6Barry E. Hurwitz7Martha Daviglus8Carlos J. Rodriguez9Stanford Health Care Oakland CADepartment of Medicine Albert Einstein College of Medicine Bronx NYDepartment of Environmental Sciences and Engineering University of North Carolina Chapel Hill NCDepartment of Medicine Albert Einstein College of Medicine Bronx NYDepartment of Social Medicine University of North Carolina School of Medicine Chapel Hill NCInstitute for Minority Health Research University of Illinois Chicago ILDepartment of Biostatistics University of North Carolina Gillings School of Global Public Health Chapel Hill NCBehavioral Medicine Research Center, Miller School of Medicine University of Miami FLInstitute for Minority Health Research University of Illinois Chicago ILDepartment of Medicine Albert Einstein College of Medicine Bronx NYBackground Our objective was to determine associations of occupational exposures with cardiac structure and function in Hispanic/Latino adults. Methods and Results Employed participants were included (n=782; 52% women, mean age 52.9 years). Occupational exposures to burning wood, vehicle exhaust, solvents, pesticides, and metals at the current and longest‐held job were assessed by questionnaire. Survey multivariable linear regression analyses were used to model the relationship of each self‐reported exposure with echocardiographic measures of cardiac structure and function. Exposure to burning wood at the current job was associated with decreased left ventricular (LV) ejection fraction (−3.1%; standard error [SE], 1.0 [P=0.002]). When the analysis was restricted to exposure at the longest‐held job, occupational exposure to burning wood was associated with increased LV diastolic volume (6.7 mL; SE, 1.6 [P<0.0001]), decreased LV ejection fraction (−2.7%; SE, 0.6 [P<0.0001]), worse LV global longitudinal strain (1.0%; SE, 0.3 [P=0.0009]), and decreased right ventricular fractional area change (−0.02; SE, 0.004 [P<0.001]). Exposure to pesticides was associated with worse average global longitudinal strain (0.8%; SE, 0.2 [P<0.0001]). Exposure to metals was associated with worse global longitudinal strain in the 2‐chamber view (1.0%; SE, 0.5 [P=0.04]), increased stroke volume (3.6 mL; SE, 1.6 [P=0.03]), and increased LV mass indexed to BSA (9.2 g/m2; SE, 3.8 [P=0.01]) or height (4.4 g/m2.7; SE, 1.9 [P=0.02]). Conclusions Occupational exposures to burning wood, vehicle exhaust, pesticides, and metals were associated with abnormal parameters of LV and right ventricular systolic function. Reducing exposures to toxic chemicals and particulates in the workplace is a potential opportunity to prevent cardiovascular disease in populations at risk.https://www.ahajournals.org/doi/10.1161/JAHA.120.016122air pollutionechocardiographyenvironmental medicineoccupational medicine |
| spellingShingle | Melissa S. Burroughs Peña Jean Claude Uwamungu Catherine M. Bulka Katrina Swett Krista M. Perreira Mayank M. Kansal Matthew Shane Loop Barry E. Hurwitz Martha Daviglus Carlos J. Rodriguez Occupational Exposures and Cardiac Structure and Function: ECHO‐SOL (Echocardiographic Study of Latinos) Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease air pollution echocardiography environmental medicine occupational medicine |
| title | Occupational Exposures and Cardiac Structure and Function: ECHO‐SOL (Echocardiographic Study of Latinos) |
| title_full | Occupational Exposures and Cardiac Structure and Function: ECHO‐SOL (Echocardiographic Study of Latinos) |
| title_fullStr | Occupational Exposures and Cardiac Structure and Function: ECHO‐SOL (Echocardiographic Study of Latinos) |
| title_full_unstemmed | Occupational Exposures and Cardiac Structure and Function: ECHO‐SOL (Echocardiographic Study of Latinos) |
| title_short | Occupational Exposures and Cardiac Structure and Function: ECHO‐SOL (Echocardiographic Study of Latinos) |
| title_sort | occupational exposures and cardiac structure and function echo sol echocardiographic study of latinos |
| topic | air pollution echocardiography environmental medicine occupational medicine |
| url | https://www.ahajournals.org/doi/10.1161/JAHA.120.016122 |
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