Protocolised way to cope with anatomical changes in head & neck cancer during the course of radiotherapy
Introduction: During a course of radiotherapy for head-and-neck-cancer (HNC), non-rigid anatomical changes can be observed on daily Cone Beam CT (CBCT). To objectify responses to these changes, we use a decision support system (traffic light protocol). Action levels orange and red may lead to re-pla...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2019-12-01
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| Series: | Technical Innovations & Patient Support in Radiation Oncology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405632419300204 |
| _version_ | 1818996139836309504 |
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| author | Suzanne van Beek Marcel Jonker Olga Hamming-Vrieze Abrahim Al-Mamgani Arash Navran Peter Remeijer Jeroen B. van de Kamer |
| author_facet | Suzanne van Beek Marcel Jonker Olga Hamming-Vrieze Abrahim Al-Mamgani Arash Navran Peter Remeijer Jeroen B. van de Kamer |
| author_sort | Suzanne van Beek |
| collection | DOAJ |
| description | Introduction: During a course of radiotherapy for head-and-neck-cancer (HNC), non-rigid anatomical changes can be observed on daily Cone Beam CT (CBCT). To objectify responses to these changes, we use a decision support system (traffic light protocol). Action levels orange and red may lead to re-planning. The purpose of this study was to evaluate how often re-planning was done for non-rigid anatomical changes, which anatomical changes led to re-planning and in which subgroups of patients treatment adaptation was deemed necessary. Materials and methods: A consecutive series of 388 HNC patients were retrospectively selected using the digital log of CBCT scans. The logs were analyzed for the number of new plans on an original planning CT scan (O-pCT) or a new pCT scan (N-pCT). Reasons for re-planning were categorized into: target volume increase/decrease, body contour decrease/increase and local shift of target volume. Subgroup analysis was performed to investigate relative differences of re-planning between treatment modalities. Results: For 33 patients the treatment plan was adapted due to anatomical changes, resulting in 37 new plans in total. Re-planning on a N-pCT with complete re-delineation was done 22 times. In fifteen cases a new plan was created after adjustment of contours on the O-pCT. Main reasons for re-planning were target volume increase, body contour decrease and local shifts of target volume. Most re-planning (23%) was seen in patients treated with chemoradiotherapy. Conclusion: Visual detection of anatomical changes on CBCT during treatment of HNC, results in re-planning in 1 out of 10 patients. Keywords: Head and neck cancer, Cone beam CT, Image guided radiotherapy, Traffic light protocol, Anatomical changes, Adaptive delivery |
| first_indexed | 2024-12-20T21:25:00Z |
| format | Article |
| id | doaj.art-4029f30d0c5440c48aae6504522678ee |
| institution | Directory Open Access Journal |
| issn | 2405-6324 |
| language | English |
| last_indexed | 2024-12-20T21:25:00Z |
| publishDate | 2019-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Technical Innovations & Patient Support in Radiation Oncology |
| spelling | doaj.art-4029f30d0c5440c48aae6504522678ee2022-12-21T19:26:10ZengElsevierTechnical Innovations & Patient Support in Radiation Oncology2405-63242019-12-01123440Protocolised way to cope with anatomical changes in head & neck cancer during the course of radiotherapySuzanne van Beek0Marcel Jonker1Olga Hamming-Vrieze2Abrahim Al-Mamgani3Arash Navran4Peter Remeijer5Jeroen B. van de Kamer6Corresponding author.; Department of Radiation Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the NetherlandsDepartment of Radiation Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the NetherlandsDepartment of Radiation Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the NetherlandsDepartment of Radiation Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the NetherlandsDepartment of Radiation Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the NetherlandsDepartment of Radiation Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the NetherlandsDepartment of Radiation Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the NetherlandsIntroduction: During a course of radiotherapy for head-and-neck-cancer (HNC), non-rigid anatomical changes can be observed on daily Cone Beam CT (CBCT). To objectify responses to these changes, we use a decision support system (traffic light protocol). Action levels orange and red may lead to re-planning. The purpose of this study was to evaluate how often re-planning was done for non-rigid anatomical changes, which anatomical changes led to re-planning and in which subgroups of patients treatment adaptation was deemed necessary. Materials and methods: A consecutive series of 388 HNC patients were retrospectively selected using the digital log of CBCT scans. The logs were analyzed for the number of new plans on an original planning CT scan (O-pCT) or a new pCT scan (N-pCT). Reasons for re-planning were categorized into: target volume increase/decrease, body contour decrease/increase and local shift of target volume. Subgroup analysis was performed to investigate relative differences of re-planning between treatment modalities. Results: For 33 patients the treatment plan was adapted due to anatomical changes, resulting in 37 new plans in total. Re-planning on a N-pCT with complete re-delineation was done 22 times. In fifteen cases a new plan was created after adjustment of contours on the O-pCT. Main reasons for re-planning were target volume increase, body contour decrease and local shifts of target volume. Most re-planning (23%) was seen in patients treated with chemoradiotherapy. Conclusion: Visual detection of anatomical changes on CBCT during treatment of HNC, results in re-planning in 1 out of 10 patients. Keywords: Head and neck cancer, Cone beam CT, Image guided radiotherapy, Traffic light protocol, Anatomical changes, Adaptive deliveryhttp://www.sciencedirect.com/science/article/pii/S2405632419300204 |
| spellingShingle | Suzanne van Beek Marcel Jonker Olga Hamming-Vrieze Abrahim Al-Mamgani Arash Navran Peter Remeijer Jeroen B. van de Kamer Protocolised way to cope with anatomical changes in head & neck cancer during the course of radiotherapy Technical Innovations & Patient Support in Radiation Oncology |
| title | Protocolised way to cope with anatomical changes in head & neck cancer during the course of radiotherapy |
| title_full | Protocolised way to cope with anatomical changes in head & neck cancer during the course of radiotherapy |
| title_fullStr | Protocolised way to cope with anatomical changes in head & neck cancer during the course of radiotherapy |
| title_full_unstemmed | Protocolised way to cope with anatomical changes in head & neck cancer during the course of radiotherapy |
| title_short | Protocolised way to cope with anatomical changes in head & neck cancer during the course of radiotherapy |
| title_sort | protocolised way to cope with anatomical changes in head neck cancer during the course of radiotherapy |
| url | http://www.sciencedirect.com/science/article/pii/S2405632419300204 |
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