Treating Children and Adolescents with Obesity: Predictors of Early Dropout in Pediatric Weight-Management Programs

Background: Possible therapeutic failure of pediatric obesity is influenced by the high dropout rate. The aim of this study was to evaluate the rate of dropout and the rate of weight loss over the 24 months of follow-up. Methods: The retrospective, single-center study, involved 489 patients followed...

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Main Authors: Giovanni Luppino, Malgorzata Wasniewska, Celeste Casto, Chiara Ferraloro, Alessandra Li Pomi, Giorgia Pepe, Letteria Anna Morabito, Angela Alibrandi, Domenico Corica, Tommaso Aversa
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Children
Subjects:
Online Access:https://www.mdpi.com/2227-9067/11/2/205
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author Giovanni Luppino
Malgorzata Wasniewska
Celeste Casto
Chiara Ferraloro
Alessandra Li Pomi
Giorgia Pepe
Letteria Anna Morabito
Angela Alibrandi
Domenico Corica
Tommaso Aversa
author_facet Giovanni Luppino
Malgorzata Wasniewska
Celeste Casto
Chiara Ferraloro
Alessandra Li Pomi
Giorgia Pepe
Letteria Anna Morabito
Angela Alibrandi
Domenico Corica
Tommaso Aversa
author_sort Giovanni Luppino
collection DOAJ
description Background: Possible therapeutic failure of pediatric obesity is influenced by the high dropout rate. The aim of this study was to evaluate the rate of dropout and the rate of weight loss over the 24 months of follow-up. Methods: The retrospective, single-center study, involved 489 patients followed for obesity in the period 2016–2020. Patients’ auxological data and blood samples were collected during the first (V1) and last visit (V2). Dropout was defined as a follow-up of less than 12 months and/or including less than one visit every 6 months. Patients were divided into two groups and compared: Group A of dropout (297 patients) and Group B of non-dropout (192 patients). Results: In the follow-up period, which had a mean duration of 24 months, the dropout rate was 60.7%. In Group A, the percentage of patients with BMI ≥ 3 SD at V2 was significantly higher than that in Group B. In Group B, the percentage of patients with pathological HOMA-IR and with fasting glucose >100 mg/dL was higher than group A. The probability of dropout was positively associated with pubertal stage and negatively with impaired fasting glycemia and pathological insulinemia at V1. Conclusion: The study demonstrated a high dropout rate during follow-up, mainly among adolescents and patients with no glucometabolic alterations.
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spelling doaj.art-402e8bea03394405bf54340de740daaf2024-02-23T15:12:23ZengMDPI AGChildren2227-90672024-02-0111220510.3390/children11020205Treating Children and Adolescents with Obesity: Predictors of Early Dropout in Pediatric Weight-Management ProgramsGiovanni Luppino0Malgorzata Wasniewska1Celeste Casto2Chiara Ferraloro3Alessandra Li Pomi4Giorgia Pepe5Letteria Anna Morabito6Angela Alibrandi7Domenico Corica8Tommaso Aversa9Department of Human Pathology of Adulthood and Childhood, University of Messina, Via Consolare Valeria 1, 98125 Messina, ItalyDepartment of Human Pathology of Adulthood and Childhood, University of Messina, Via Consolare Valeria 1, 98125 Messina, ItalyDepartment of Human Pathology of Adulthood and Childhood, University of Messina, Via Consolare Valeria 1, 98125 Messina, ItalyDepartment of Human Pathology of Adulthood and Childhood, University of Messina, Via Consolare Valeria 1, 98125 Messina, ItalyDepartment of Human Pathology of Adulthood and Childhood, University of Messina, Via Consolare Valeria 1, 98125 Messina, ItalyDepartment of Human Pathology of Adulthood and Childhood, University of Messina, Via Consolare Valeria 1, 98125 Messina, ItalyPediatric Unit, AOU Policlinico G. Martino, Via Consolare Valeria 1, 98125 Messina, ItalyDepartment of Economics, University of Messina, 98125 Messina, ItalyDepartment of Human Pathology of Adulthood and Childhood, University of Messina, Via Consolare Valeria 1, 98125 Messina, ItalyDepartment of Human Pathology of Adulthood and Childhood, University of Messina, Via Consolare Valeria 1, 98125 Messina, ItalyBackground: Possible therapeutic failure of pediatric obesity is influenced by the high dropout rate. The aim of this study was to evaluate the rate of dropout and the rate of weight loss over the 24 months of follow-up. Methods: The retrospective, single-center study, involved 489 patients followed for obesity in the period 2016–2020. Patients’ auxological data and blood samples were collected during the first (V1) and last visit (V2). Dropout was defined as a follow-up of less than 12 months and/or including less than one visit every 6 months. Patients were divided into two groups and compared: Group A of dropout (297 patients) and Group B of non-dropout (192 patients). Results: In the follow-up period, which had a mean duration of 24 months, the dropout rate was 60.7%. In Group A, the percentage of patients with BMI ≥ 3 SD at V2 was significantly higher than that in Group B. In Group B, the percentage of patients with pathological HOMA-IR and with fasting glucose >100 mg/dL was higher than group A. The probability of dropout was positively associated with pubertal stage and negatively with impaired fasting glycemia and pathological insulinemia at V1. Conclusion: The study demonstrated a high dropout rate during follow-up, mainly among adolescents and patients with no glucometabolic alterations.https://www.mdpi.com/2227-9067/11/2/205adolescentdropoutglucometabolic alterationsobesitypediatrics
spellingShingle Giovanni Luppino
Malgorzata Wasniewska
Celeste Casto
Chiara Ferraloro
Alessandra Li Pomi
Giorgia Pepe
Letteria Anna Morabito
Angela Alibrandi
Domenico Corica
Tommaso Aversa
Treating Children and Adolescents with Obesity: Predictors of Early Dropout in Pediatric Weight-Management Programs
Children
adolescent
dropout
glucometabolic alterations
obesity
pediatrics
title Treating Children and Adolescents with Obesity: Predictors of Early Dropout in Pediatric Weight-Management Programs
title_full Treating Children and Adolescents with Obesity: Predictors of Early Dropout in Pediatric Weight-Management Programs
title_fullStr Treating Children and Adolescents with Obesity: Predictors of Early Dropout in Pediatric Weight-Management Programs
title_full_unstemmed Treating Children and Adolescents with Obesity: Predictors of Early Dropout in Pediatric Weight-Management Programs
title_short Treating Children and Adolescents with Obesity: Predictors of Early Dropout in Pediatric Weight-Management Programs
title_sort treating children and adolescents with obesity predictors of early dropout in pediatric weight management programs
topic adolescent
dropout
glucometabolic alterations
obesity
pediatrics
url https://www.mdpi.com/2227-9067/11/2/205
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