Efficacy of Synthetic Peptide Corresponding to the ACTH-Like Sequence of Human Immunoglobulin G1 in Experimental Autoimmune Encephalomyelitis
Peptide immunocortin sequence corresponds to the amino acid residues 11–20 of the variable part of human immunoglobulin G1 (IgG1) heavy chain. Since immunocortin was shown previously to inhibit phagocytosis in peritoneal macrophages and ConA-induced T-lymphocytes proliferation in culture, we suggest...
Main Authors: | Valery I. Turobov, Alexey V. Danilkovich, Alexei B. Shevelev, Yulia K. Biryukova, Natalia V. Pozdniakova, Viatcheslav N. Azev, Arkady N. Murashev, Valery M. Lipkin, Igor P. Udovichenko |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-02-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fphar.2018.00113/full |
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