Application of Twin Screw Extrusion in the Manufacture of Cocrystals, Part I: Four Case Studies

Application of Twin Screw Extrusion in the Manufacture of Cocrystals, Part I: Four Case Studies

The application of twin screw extrusion (TSE) as a scalable and green process for the manufacture of cocrystals was investigated. Four model cocrystal forming systems, Caffeine-Oxalic acid, Nicotinamide-trans cinnamic acid, Carbamazepine-Saccharin, and Theophylline-Citric acid, were selected for the...

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Bibliographic Details
Main Authors: Karthik Nagapudi, Fernando Alvarez-Núñez, Robert Saw, Cesar Medina, Dominick Daurio
Format: Article
Language:English
Published: MDPI AG 2011-08-01
Series:Pharmaceutics
Subjects:
twin screw extrusion
cocrystals
environmentally friendly
green chemistry
Online Access:http://www.mdpi.com/1999-4923/3/3/582/

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http://www.mdpi.com/1999-4923/3/3/582/

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