MMF/MPA Is the Main Mediator of a Delayed Humoral Response With Reduced Antibody Decline in Kidney Transplant Recipients After SARS-CoV-2 mRNA Vaccination

MMF/MPA Is the Main Mediator of a Delayed Humoral Response With Reduced Antibody Decline in Kidney Transplant Recipients After SARS-CoV-2 mRNA Vaccination

Kidney transplant recipients (KTR) show significantly lower seroconversion rates after SARS-CoV-2 mRNA vaccination compared to dialysis patients (DP). Mycophenolate mofetil or mycophenolic acid (MMF/MPA) in particular has been identified as a risk factor for seroconversion failure. While the majorit...

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Bibliographic Details
Main Authors: Julian Stumpf, Torsten Siepmann, Jörg Schwöbel, Grit Glombig, Alexander Paliege, Anne Steglich, Florian Gembardt, Friederike Kessel, Hannah Kröger, Patrick Arndt, Jan Sradnick, Kerstin Frank, Anna Klimova, René Mauer, Torsten Tonn, Christian Hugo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Medicine
Subjects:
vaccination
kidney transplant recipients
SARS-CoV-2
humoral response
mycophenolic acid
clinical decision making
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.928542/full

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https://www.frontiersin.org/articles/10.3389/fmed.2022.928542/full

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